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Friday, October 08, 2010 ANDREA asks

Q: WHAT IS THE SIGNIFICANCE OF A CA 125.MY FIRST TEST PRIOR TO CHEMO AND RADIATION WAS 126. MY NEW ONE IS AT 46. DOES THAT MEAN THERE IS STILL CANCER PRESENT?

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Answers (1)
Phyllis Johnson, Health Guide
10/ 8/10 6:53pm

Andrea, the CA 125 test is mainly used to monitor ovarian cancer patients' progress during treatment.  It is a type of test called a tumor marker.  The problem with tumor marker tests is that they are not consistently reliable.  Some women's levels will go down after treatment and up again if they have a recurrence.  For other people fluctuations seem almost random.  The dramatic decrease in your levels may mean that your chemo and radiation has worked because although CA 125 is primarily for ovarian cancer it can also measure changes in the status for breast cancer patients.  You will want to ask your doctor how he or she is interpreting this decrease.  At this point, your doctor may feel that it is too soon to know if you are one of the people for whom the test is accurate, or he may see this test as confirmation that your treatment worked.

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10/ 9/10 9:50am

THANKS A LOT FOR YOUR ANSWER. THAT IS EXACTLY WHAT SHE SAID, BUT SHE ALSO SAID ITS NOT THAT RELIABLE IN BREASTCANCER PATIENTS. I GUESS I JUST WANTED REASSURANCE. THANKS AGAIN.  ANDREA

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Phyllis Johnson, Health Guide
10/ 9/10 11:28am

Glad to help.  Stay well!

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By ANDREA— Last Modified: 12/26/10, First Published: 10/08/10