Can you please let me know where you got the statistic of 80% of those with idc do not benefit from toxic therapy? I am 52, also IDC grade 2, stage 1, ER,PR+, HER2+ - no node involvement, and mass less than .o6 cm, oncotype score of 23. I had a bi-lateral masectomy and my doctor still wants to do chemo with herceptin, followed by AI for 5 years. I think the chemo would do more harm than good.