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Tuesday, March 09, 2010 janie r, Community Member, asks

Q: what does the FISH probes mean HER2 & CEP 17 FISH with results 1.3 negative

i have been told i have invasive carcinoma in right breast 4 to 5 CFN i had breast cancer 18 yrs ago in same breast but different type

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Answers (1)
PJ Hamel, Health Guide
3/ 9/10 9:39pm

Janie, you've offered a very small (and rather confusing) part of your pathology report here; CEP 17 is a chromosome, and HER2 is a protein; the absence or presence of abnormalities in both are assessed by the pathologist. If HER2 is positive, it means your cancer is considered more aggressive, and you'd take Herceptin; but it appears your HER2 is negative. You might want to get a copy of your pathology report, if you don't already have one, and interpret it using our Guide to Understanding Your Pathology Report ; I think that'll be a big help to you. Good luck - PJH

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By janie r, Community Member— Last Modified: 04/14/13, First Published: 03/09/10