Yes, since estrogen is a hormone, and fibrocystic change responds to hormones, this could definitely be the culprit for your sore, swollen breasts. Reprt this side effect to your doctor, and see what s/he wants you to do... Also, hopefully you'll be taking just a low dose of estrogen for a short amount of time; prolonged hormone therapy raises your risk of breast cancer, and you definitely don't want to go there! Good luck - hope the pain abates soon. PJH
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