Hi Keerti - Unfortunatley, there's no way to rule out the possibility of a recurrence. With infiltrating cancer the possibility will always be there. You can lessen it with a mastectomy. You can "lessen it less" with a lumpectomy. In other words, mastectomy would make a recurrence IN THE BREAST nearly impossible, while it wouldn't rule out a recurrence elsewhere. Lumpectomy would make a recurrence in the breast possible, as well as recurrence elsewhere possible. So, it's a roll of the dice... It's playing percentages. I'd ask your doc what the percentages of recurrence are for lumpectomy and radiation, vs. mastectomy; in either case, she'd be taking tamoxifen or an aromatse inhibitor for years afterwards, so that will help, too. Good luck - PJH