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Thursday, July 10, 2008 Ms Tiffany, Community Member, asks

Q: Difference between Taxotere and Taxol

I was originally supose to get Taxol, now Dr is saying Taxotere are they just similar or the same? Thanks in advance

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Answers (2)
PJ Hamel, Health Guide
7/10/08 8:55pm

Hi Ms.Tiffany! Hope you're doing well- I found the following good explanation on scienceblog.com:

 

Taxotere (docetaxel) and Taxol (paclitaxel) are closely related. Taxol was discovered in the USA by testing many natural compounds while Taxotere was developed in Europe as part of a programme to screen closely related compounds. Both compounds work by interfering with cell division, but there are subtle differences. When tested in tissue culture not all cancer cells are equally sensitive to both agents. There are also differences in they way they are broken down and cleared from the body. So there are reasons to believe they may have different effectiveness as anti-cancer medicines.

 

Hope the taxotere works well for you - PJH

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Laurie Kingston, Health Guide
7/11/08 9:11am

Hi-

My oncologist told me that there was a better overall response rate to Taxotere, which is why he prefers it.

Laurie

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By Ms Tiffany, Community Member— Last Modified: 06/13/12, First Published: 07/10/08