Hi - Microcalcifications, if they're randomly scattered around the breast, are something many women have; they're no problem. But when those microcalcificaitons start to group up, or form themselves into a line, they could indicate that you MAY be developing some cancer - they're almost like a cancer precursor, a shadow of what might happen. I'd guess "right in the middle" means that they're not totally randomly scattered... but they're not SO clustered, or so evidently in line, that the radiologist can say "Oh yes, these should be biopsied." Thus the watchful waiting. They'll look at them again in 6 months, and see if they're the same, or if they've clustered together more, or formed more of a definite pattern. Good luck - hope things turn out well for you. PJH