I am 57 years old and have breast cancer, stage 3. I had mastectomy, chemo, radiation and am taking Anastrozole and Vitamin D and C. After my chemo and radiation, I haven’t had any kind of lab work or blood test done to find out if my cancer cells are completely destroyed. I am concerned, because my oncology doctor said that there is a possibility of recurrence.  My radiation ended in August 2010.  Below is my diagnoses and what my pathology report states. Please help me understand the report and the risk of my cancer coming back. Thank you. My diagnoses: malignant neoplasm of breast, unspecified site (174.9) metastatic malignant neoplasm to lateral axillary lymph nodes (196.3L) estrogen receptor positive status ER+) (V86.0) My pathology report states: A) Lymph node, right axillary, level three, biopsy:metastatic ductal carcinoma involving (1) one of two (2) axillary, level 3 lymph nodes, no extranodal extension identified. B) Breast, right, mastectomy with axillary lymph nodes:infiltrative ductal carcinoma, Nottingham grade 111/111 with the following features: 1. Tumor size (infiltrating component): at least 5.4 x 5.00 x 4.00cm by gross measurement. 2. Nuclear grade:high 3. Mitotic rate: high 4. Tubular differentiation: little 5. Intraductal carcinoma component: absent 6. Calcifications:present in benign epithelial elements and fibrous stroma. 7. Intramammary lymphatic space invasion: present and extensive 8. Resection margins:negative for malignancy; closest margin deep, 0.5 cm 9. Breast marker status, performed at ARUP laboratory on previous breast needle biopsy (09-38440S) with the following results: a. Estrogen receptor: Borderline 20% b. progesterone receptor:negative c. HER 2NEU (c-erbB-2)2+by IHC and non-amplified by fish analysis. 10. Additional pathologic findings: a. proliferative fibrocystic change with focal benign ductal hyperplasia, duct ectasia,columnar cell change and adenosis. 11. Axillary lymph node status:metastatic ductal carcinoma involving seventeen (17) of nineteen (19) right axillary lymph nodes with the following features: a. extranodal extension present b. largest lymph node involvement 5.5 cm in greatest dimension. COMMENT: Taking all right axillary lymph nodes together, metastatic tumore involves eighteen (18) of twenty one (21) right axillary nodes to include level 3 lymph nodes. 12. Pathologic stage:pT3,pN3a, pMX SOURCE: a). R. axillary node level 3 B) R. breast & axillary content. The lymph node candidates are entirely submitted as follows: A1) smaller lymph node candidate A2) larger lymph node candidate.