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Thursday, February 17, 2011 BCsurvivor, Community Member, asks

Q: Can Herceptin cause a change in your cholestoral level. I have always had excellect HDL and LDL Cholesterol , but since I've been on Herceptin, my LDL went up.

This past year, at age 49, I was diagnosed with Er- Pr-Her2neu 3+ breast cancer. It was early stage but, I opted to have the adjuvant therapy which consisted of 12 weeks of Taxol and Herceptin. After the 12 weeks chemo and Herceptin, I continued getting infusions of Herceptin every three weeks. I am still in treatment. This past week, I had my annual physical and found out my LDL Cholesterol went up several points. Other than taking time off to recover from the surgeries and chemo,I have always been active, working out several times per week, and being mindful of what I eat. I don’t smoke or drink. I stay away from high fat foods and red meat and pork. I just don’t understand why my cholesterol #’s went up. My HDL is 62 and my LDL is 128, the highest it’s ever been.
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Answers (1)
PJ Hamel, Health Guide
2/17/11 2:37pm

Hi - While I've never heard of Herceptin raising your cholesterol level, that doesn't mean it can't happen; we each have our own side effects. We're not doctors here, simply well-read breast cancer survivors; I'd suggest this is an issue you might want to talk with your oncologist about. S/he should be able to advise you on how (or if) you should treat this. Good luck - PJH

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By BCsurvivor, Community Member— Last Modified: 02/17/11, First Published: 02/17/11