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Thursday, July, 24, 2008

Question
Honie Golden
05/12/08
Honie Golden
Category:Chemotherapy

Is TC chemotherapy as effective as CMF chemotherapy?

I am 40 yrs old and recently had a lumpectomy to remove a 1.4cm invasive ductal carcinoma and now am faced with choosing a chemotherapy regime.  My nodes were negative and the tumor was ER positive (35%).  The oncologist wants me to choose between 4 rounds of TC chemotherapy and 6 months of CMF chemotherapy.  Any guidance on how to pick between the 2 would be appreciated!

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Answers (2)
PJ Hamel
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Monday, May 12, 2008

Honie, ask your doctor if you can have the Oncotype-DX test, which predicts how effective certain kinds of chemotherapy will be for you. I know more and more women are finding that this test has really helped them make a decision.

 

For more information about CMF, see our FAQS:

http://www.healthcentral.com/breast-cancer/c/78/10884/chemo-faqs-cmf/

 

As for TC, I don't know what that is - haven't heard of it. But take a look at this FAQ on AC+ T chemo:

http://www.healthcentral.com/breast-cancer/c/78/10887/ac-act-tac/

 

Hope this helps, Honie. Good luck -PJH

June Chan
Sunday, June 15, 2008

Hi,

I had the oncotype DX test done. My score was 27- an intermediate result meaning I have a 17% chance of recurrence in 10 years. So additional TC adjuvant chemotherapy will give me an added 5% reduction in possible metastasis over 10 years. My oncologist thought that this number is worth going through TC chemo. (Mastectomy, no nodal involvement, ER/PR positive, HER2 negative, 3.5 cm mucinous breast cancer).

You should start adjuvant chemo within 8 weeks of your lumpectomy. My first chemo was on June 3, 2008. The TC protocol went surprisingly smoothly. It felt like a 3 day flu, and I think the next 3 will go by quickly. I am 52 years old and only missed one day of work so far.

 

Good luck with your decision. TC chemo seems very do-able to me.

June Chan

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