There's a clinical trial underway comparing TAC to TC alone, but results won't be complete for anouther 4 years; perhaps your oncologist is on the conservative side, and wants you to go with the "tried and true" TAC vs. the less-proven TC.   It looks like he's also giving you the option to participate in a trial: TAC vs. TC vs. TC/Bev (I'm sorry, I can't figure out what "Bev" is). It's true, when you're in a trial, you can't decide which of the protocols you'll receive; so joining the trial might mean getting just TC, but it also might mean you receive either of those other two options.   Some oncologists do prescribe TC for their patients. If that's what you feel you want, given the options you've researched, then your best bet would be a referral for a second opinion. See if you can access an oncologist at a Comprehensive Cancer Center. These large centers treat thousands of patients every year, and thus have lots of data about outcomes to pull from. You're more likely to find a doctor offering more chemo options there than you would be at a local hospital. Best of luck to you - PJH