Hi, I had the oncotype DX test done. My score was 27- an intermediate result meaning I have a 17% chance of recurrence in 10 years. So additional TC adjuvant chemotherapy will give me an added 5% reduction in possible metastasis over 10 years. My oncologist thought that this number is worth going through TC chemo. (Mastectomy, no nodal involvement, ER/PR positive, HER2 negative, 3.5 cm mucinous breast cancer). You should start adjuvant chemo within 8 weeks of your lumpectomy. My first chemo was on June 3, 2008. The TC protocol went surprisingly smoothly. It felt like a 3 day flu, and I think the next 3 will go by quickly. I am 52 years old and only missed one day of work so far.   Good luck with your decision. TC chemo seems very do-able to me. June Chan