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Cancer itself might tend to be depressing, Barbara; it's quite a blow. And I know some women become depressed taking tamoxifen, so it may have something to do with lack of hormones, too. I hope you're being treated for it - luckily, doctors do have a pretty good handle on how to treat depression. And, as you said in your question, stopping Arimidex may be an option as well. Good luck - hope you feel better in the near future. PJH

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