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Tuesday, March 09, 2010 bewildered asks

Q: I had lumpectomy for stage 1, grade 2, ER+, PR+, Her2+ Breast CA

I had lumpectomy for breast cancer on 2/2/10 for stage 1, grade 2, ER & PR+, Her2+, size was 1.6 tumor and was recommended today for tx of TCH every 3 weeks x6, continuing herceptin for a year.Also, tamoxifen and have radiation .  Is this the recommended tx for this dx?

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Answers (2)
PJ Hamel, Health Guide
3/10/10 4:27am

Hi - You don't say if any lymph nodes showed cancer, which would pretty much guarantee chemo. But being HER2+ is also pretty much a chemo guarantee, as it signals a somewhat more aggressive cancer.

 

This all sounds like the standard of care for your diagnosis. Lumpectomy and radiation are nearly always delivered in tandem (radiation following chemo, probably); Herceptin is a given for HER2+; and tamoxifen will take care of the ER/PR+ (I'm assuming you're pre-menopausal, otherwise you'd be offered an aromatase inhibitiro in place of tamoxifen). The only thing you MIGHT explore, if you're uncomfortable with this treatment plan, would be the Oncotype DX test, which would tell you just how much chemo is likely to help (or not help) you.

 

Good luck, and stay in touch here - we can help. PJH

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3/19/10 6:33pm

Dear Bewildered - I was exactly the same diagnosis!  If there was no lymph node involvement, you really need to get the Oncotype DX test to see if you score high, medium or low for recurrence.  (I was medium low which is classified as a betweener, meaning doctors really don't know how to interpret it).   Also, you can take the Herceptin treatment w/o chemo, (it isn't considered the traditional treatment but you can find doctors who will work with you), and the facts speak for themselves.  Chemo has been around since WWII and the mortality rate for breast cancer has dropped hardly more than 1%, vs. since Herceptin has come on the market, it reduces your risk of recurrence rate by 50%, so if your recurrrence rate is 10%, it reduces it to 5%.  Bottom line - please do your homework and understand what the numbers/statistics are really telling you.   For example, if your recurrence rate risk is only 3%, do you really want to subject your body to chemo understanding all the risks or serious side effects that can occur with it?   The more information you have, the more confident you will feel about your decision.  Personally I'm all about quality vs. quantity....Stay Strong!

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By bewildered— Last Modified: 12/25/10, First Published: 03/09/10