I am 49 years old. This past January I had surgery for DCIS. I was diagnosed with IDC after having a lumplectomy, early stage T1a, Nuclear grade high (3), Her2 + (3+), er-pr-breast cancer. The margins were not clear, so I had a reexcision and a Sentinal Node Biopsy. (Partial Mastectomy right breast). The margins still were not clear, and more DCIS was found in other parts of my breast, so I was told I needed a mastectomy. The good news was the Lynph Nodes were negative.

With my risk factors, I opted for a bilateral. On March 10, 2010 I had a double mastectomy and expanders put in for reconstruction.

I just saw my Oncologist on March 19th. She informed me that she recommends chemo and Heceptin and told me I am a good candidate for a Phase II Trial of Adjuvant Paclitaxel (Taxol) and Trastuzumab (Herceptin) for Node Neg Her2- Positive Breast Cancer. The other option if I choose not to go with the trial would be "TCH" Taxotere, Cacbablalin, and Herceptin (every 3 wks x6 (18weeks or 4.5 months) and Herceptin every 3 weeks for 7.5 months after that. The trial would be:  Taxol & Herceptin given IV every week for 12 weeks. Then I would then received Herceptin every 3 weeks or weekly for 4o weeks. I was told the trial would be easier to tolerate, and not as toxic. What are some quetions I should ask my doctor on April 2 when I see her again to help me make an informed decision.

Thank you for your help

bcsurvior