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Wednesday, July 15, 2009 lauren09 asks

Q: what is grade 3? 1)ductal carcinoma grade 3 with lymphatic invas.2)axillary node revaled metastatic

My sister is 40 years old, with 3 teenage children. She has had a long history of ovarian cyst since she was 16.  At the age of 30 she was diagnosed with multiple fibroids in her uterus. The doctor recommended a hysterectomy to solve both her fibroid, and large ovarian cyst problems. However, a day ago my sister was diagnosed with breast cancer.

1), 2 lumps @ 1.5 invasive mass ductal carcinoma grade 3 with lymphatic invasion

2). 1 lump     enlarged left auxiliary node revealed metastasis carcinoma

3). Pending further testing of the enlarged auxiliary node metastasis carcinoma

 

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Answers (2)
7/15/09 11:37am

Hi Lauren. Ductal carcinoma is cancer that occurs in the milk ducts of the breast. It is described as invasive when it has infiltrated surrounding breast tissue. Grade 3 means that it is aggressive, which is why it has reached the lymph nodes in the armpit and is consistent with how breast cancer behaves in younger women. I would imagine her doctors will order scans of her brain, liver and bones to discover if there are any distant metastases - i.e cancer cells in other parts of her body. If they haven't done so, make sure she asks why. There will be lots of tests and they should be done without delay.

 

I would also expect that they will prescribe some aggressive treatment involving chemo, surgery and radiation. She has a tough few months ahead of her, but she will have your support and there are many other sources of support around from other women who have been through it. This website is excellent for that. You might like to suggest to her that she become involved here and help her find the time to do so by keeping an eye on her kids. Your help will be invaluable to her, but I know from experience that you really need to speak to other women who have been through breast cancer themselves.

 

My very best wishes and positive thoughts to you both.

 

Sue

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7/14/10 10:14pm

I'm not sure how to use this site - first time.  I was just diagnosed and it sounds similar to your sister.  I hope she is okay.  I am looking for a more detailed description of my path report because I think I was only half awake when they were talking to me.  I have IDC with micropapillary lymphovascular features.  The grade is a III and venous/lymphatic says present.  My node is only 1.4.  I thought that since IDC was the most common type that this would be pretty easy but now that I am interpreting the rest of this report and I concerned even more.

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7/15/10 5:25am

Hi CJ - Welcome! Glad you found us. (Though not glad you had to...) Please read our Guide to Understanding your Pathology Report for lots of help interpreting all of the confusing information you've received. Yes, IDC is the most common type of breast cancer, so luckily, doctors have lots of experience treating it, including the data to show what treatments work best. It sounds to me like you have a "medium" serious case; not the mildest, and certainly not the worst. Millions of us have received similar diagnoses, have gone through treatment, and are living healthy lives; so hopefully you'll walk this same path. It's understandable that you're feeling pretty shocked about all of this right now; but as you get into treatment, you'll start to "normalize" and emotionally, things should settle down.

 

Please stay in touch here, OK? We can help you through this. Good luck - PJH

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7/15/10 8:02am

Thank you

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6/18/11 7:55am

my wife axilary node was sent for biopsy which revealed poorly differentiated carcinoma with invasive ductal carcinoma so the mrm was done and sent for biopsy which revealed  metastatic carcinoma on 9 nodes out of 16 sent the total measurment was 0.6x0.6 cm or say 200 cell  with grade iii 3rd carcinoma  why the original biopsy had differance however let me know what is the progonisis now the cancer hospital suggested ER/PR AND NR NEU.........SUGGEST  TREATIBALE  WHAT SHOUDL BE THE TREATMENT AND IS LIFE EXPECTANCY HOPE FULL AND MOREOVER SHE IS MORE THAN 60 WITH DIABETESE....... MOHAMMAD SHAFI

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6/18/11 8:54am

Mohammad, with successful treatment, your wife's prognosis should be fairly good. Many women survive breast cancer these days; it's not the scary situation it used to be. It sounds like your hospital is giving you good advice; that they need to determine her hormone receptivity (ER/PR), and whether she's HER2-neu positive (if they haven't already done this). Both of those tests will help inform the best treatment for her.In the meantime, you might find our post on invasive ductal carcinoma (IDC) helpful.

 

I'm not a doctor, but it seems to me that she'd have surgery and chemotherapy, perhaps radiation; and then the possibility of long-term hormone therapy (drugs), depending on the results of the above-mentioned tests.

 

Different biopsies can have different results because they look at different tissue specimens. It's possible to have different types and degrees of breast cancer at once; in fact, it's quite common, so don't worry about those two different biopsy results, OK?

 

Best of luck to both of you as your wife goes through treatment. And stay in touch here, OK? We can help. PJH

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6/18/11 3:11pm

thanks a lot for the time you spared to make comment on my querry i m really obliged and feel morally boosted..........sure we will adopt as the doctor has suggested the course of medication  .....i convayed your comment to my wife she felt encouraged too.....may god bless you  with best wishes mohammad

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6/18/11 9:19pm

And may God bless both of you, too, Mohammad - I wish you all the best. May your wife soon be on the path to health once again- PJH

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