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Hi Angie - from my experience the ultrasound is used essentially to determine if a lump is fluid filled or solid.  I would think that if they cannot find it on an ultrasound, it may just be because it is deep within your breast tissue. A MRI, PET Scan , or Breast CT or CAT Scan are often other tools used in finding lumps.  Sometimes the do one, sometimes they do ALL - which can be a pain, but at least it gives them a view from every angle and lets you know what to expect.   Good luck to you figuring out what that lump is! Angi