We are advised that Abraxane must be administered within 2 hours of mixing. I.e., when the lyophilyzed Abraxane is made into solution by adding saline and then put into a 500 cc IV bag of NS, we are advised by one home infusion service that they will not do it because the solution must be administered within 2 hours of mixing. I am a physician (Breast Surgical Oncologist) with experience and facility with reconstituting drugs and administering them under sterile conditions. Is there some reason why I could not reconstitute the Abraxane at home for delivery to the patient either by myself or by a home infusion nurse?





