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Saturday, May 01, 2010 Kimberly asks

Q: Question about Femara

I am 41 years old and have breast cancer.  I am BRCA 2 positive.  I just finished 4 months of chemotherapy.  In 5 weeks time I will have my surgeries  (removal of breasts, uterus, cervix, falopian tubes, and ovaries).  In the mean time I will begin taking an estrogen blocker called Femara.  I know this is a relatively new drug.  If anyone has taken it or researched it I would be so appreciative of any advice regarding the side effects.   How does one maintain a balanced self when completed deprived of estrogen?  I am entering menopause early due to my treatments.  I know I need to do this to be cancer free but I am worried about my moods and emotions shifting.  I want to remain being my happy, positive self and mommy to my 3 young ones.   Thank You!

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Answers (2)
PJ Hamel, Health Guide
5/ 1/10 8:49am

Hi - Femara actually isn't a new drug - it's part of the famly of aromatase inhibitors, which have been in wide usage for 6-7 years, and less wide usage before that. Please read our aromatase inhibitor FAQS for more information about how it works, and possible side effects.

 

In fact, you're not depriving yourself of estrogen 100%. Your body still makes it, via the adrenal glands, I believe. Femara will prevent your body from using most of that estrogen, though; that's what an AI does.

 

Read up on menopause, because that in fact will be the range of side effects you may experience. You'll want to have a baseline DEXA scan, to track possible bone loss due to estrogen deprivation and Femara, which promotes bone loss. Other than that - exercise is a big help, in a variety of ways, both emotional and physical. If you find you're hit with mood swings and depression, definitely see a doctor about possible drug treatment; it's not a "failure" to take an antidepressant! It's natural to feel bad at times, considering what you're going through. But if these lows become constant, you'll want to treat them.

 

And there's no saying that will happen to you. I went through chemical menopause, took Arimidex for 5 years, and never felt any depression or had mood swings. So if you're a happy mom now, chances are you'll remain so - once you have a few months of adjustments behind you, perhaps.

 

Good luck - PJH

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5/ 1/10 11:46pm

Hey Kimberly,

 

I've been taking Femara for 6 1/2 months and I'm by no means an expert.  However, I can say that the side effects will vary from perosn to person, so don't go into this with a mindset that you will have mood swings.  I agree with PJ that if you are happy now, you will continue to be so.  You may experience weepy sessions, but who wouldn't going through what you are?  I did find myself more prone to tears during sappy movies (I was trying to distract myself).  The overwhelming sadness I felt had as much to do with discovering the cancer as the Femara.  The moodiness lasted only a few weeks.  My normal cheerfulness returned as soon as my grandchildren came for a visit.  Keep busy, keep moving and know that every side effect means that the medicine is working for you.  Enjoy your children, they are really your best medicine.  Take care.

 

Truckee

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By Kimberly— Last Modified: 12/25/10, First Published: 05/01/10