My wife was just diagnosed with Stage 3 A breast cancer and they are recommending Avactin.

John, Avastin has just very recently been approved for treatment of women who are "triple negative" (i.e., not estrogen- or progesterone-receptive, not HER2-neu receptive), because after chemo, there's no hormone therapy these women can take that's effective. I don't have personal experience with it, but a friend of mine did the protocol you're talking about - chemo followed by Avastin - and she was pleased at the lack of side effects from the Avastin. She finished taking it about 8 months ago, and is doing fine. FYI, ACT is currently one of the most common types of chemo, so the docs have had lots of experience with it - which is a good thing.

Anyone else out there have any experience with ACT followed by Avastin they can share with John? - PJH

John, It's been ten years since I was diagnosed with Stage IIIB inflammatory breast cancer, so I didn't have Avastin myself although I had the three drugs in ACT chemo.  I know (via email) lots of people who have had wonderful results from Avastin.  Like any cancer diagnosis, a Stage III diagnosis is scary, but lots of women do get well.  Keep asking questions so you understand what is happening, and you will get through this.