Cytoxan Oral

Cytoxan Oral Side Effects

Nausea, vomiting, loss of appetite, stomach ache, diarrhea, or darkening of the skin/nails may occur. Nausea and vomiting can be severe. In some cases, drug therapy may be necessary to prevent or relieve nausea and vomiting. Changes in diet such as eating several small meals or limiting activity may help lessen some of these effects. If these effects persist or worsen, notify your doctor or pharmacist promptly.

Temporary hair loss may occur. Hair growth should return after treatment has ended or may even return during treatment. However, new hair may have a different color or texture.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

• pink/bloody urine
• unusual decrease in the amount of urine
• mouth sores
• unusual tiredness or weakness
• joint pain
• easy bruising/bleeding
• stopping of menstrual periods
• existing wounds that are slow healing

Tell your doctor immediately if any of these rare but very serious side effects occur:

• black/bloody stools
• severe stomach/abdominal pain
• yellowing eyes or skin
• dark urine
• mental/mood changes
• muscle weakness/spasm
• swelling of the ankles/feet
• sudden or unusual weight gain

This medication may rarely cause very serious effects on the heart, especially when used in high doses, or in combination with radiation treatment or certain other chemotherapy drugs (e.g., doxorubicin). Seek immediate medical attention if you develop:

• chest pain
• jaw/left arm pain
• trouble breathing
• irregular heartbeat

This medication can lower the body's ability to fight an infection. Notify your doctor promptly if you develop any signs of an infection such as fever, chills or persistent sore throat.

Cyclophosphamide may lessen the chance of having children in both men and women. Sterility is usually temporary with this medication, but can be permanent in some cases. Consult your doctor for more details.