Alternatives To Tamoxifen

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No Side Effects from Tamoxifen (Nolvadex)? Why It May Not Be Working

Research on the possibility of a drug interaction between tamoxifen (nolvadex) and serotonin reuptake inhibitors (SSRIs) - a class of drugs that includes Paxil (paroxetine) and Prozac (fluoxetine hydrochloride) - has revealed an unexpected wrinkle: A significant number of women possess a genetic trait that inhibits the benefits of tamoxifen, regardless of whether they take Paxil or other drugs.

 

Women with the trait are unable to produce an enzyme known as CYP2D6, which is needed for...

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