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How Does Tamoxifen Work In The Body?
Chemical name: Tamoxifen
Brand names: Nolvadex, Apo-Tamox, Tamofen, Tamone
Class: SERM (selective estrogen receptor modulator) hormonal therapy. Evista and Fareston are other SERMs.
How it works: SERMs block the effects of estrogen in the breast tissue by attaching to the estrogen receptors in breast cells.
Uses: Tamoxifen, used to treat men and both pre-menopausal and post-menopausal women, typically is used to:
- reduce the risk of early-stage, hormone-receptor-positive breast cancer coming...
More information on "How Does Tamoxifen Work In The Body?"
From Our Experts
Taking Tamoxifen (Nolvadex)? Why Paxil and Other Antidepressants...
Tamoxifen (or nolvadex) is a drug commonly prescribed to prevent the recurrence of breast cancer, but a common side effect of the... Read more »
Tamoxifen (Nolvadex) and Fareston FAQs: Hormone Therapies to Prevent...
Q. I was diagnosed with ER-receptive breast cancer and have had a lumpectomy and radiation. Now my oncologist has prescribed tamoxifen. I... Read more »
Breast Cancer, Depression, and Tamoxifen: A Dangerous Trio
Do you have breast cancer, or are you at high risk for it? Are you taking an antidepressant? Are you on tamoxifen?If you answered “yes”... Read more »
Tamoxifen: Personal Experience and Research Differ in Side Effects
What do you do when “clinical studies show” that something isn’t true, yet you feel, deep inside, that it is? I meet once a month... Read more »
Recurrence: Taking Tamoxifen May Not Be Enough Protection.
Breast cancer is a powerful punch to the gut, an emotional slap upside the head. Cancer is the big gorilla sitting in the corner; while... Read more »
From Our Sources
Tamoxifen Targets Estrogen Receptors
Source: Breastcancer.org
All of the female hormones interact with your cells through estrogen receptors. There are all kinds of estrogen receptors in your body, each with... Read more »
Tamoxifen
Source: Breastcancer.org
Tamoxifen, the generic name of Nolvadex, is the oldest and most-prescribed SERM. Tamoxifen is approved by the U.S. Food and Drug Administration (FDA)... Read more »
Q&A: Can Antidepressants Interfere With Tamoxifen?
A breast cancer patient asks Dr. Mitchell Hecht if her antidepressant will interfere with the drug tamoxifen. According to Dr. H, SSRI drugs like... Read more »
Antidepressants may make tamoxifen less effective
Statistics show that many breast cancer survivors take antidepressants to help control the hot flashes brought on by the use of the drug tamoxifen, a... Read more »
Protein may cause tamoxifen resistance
Tamoxifen is one of the most widely used breast cancer drugs. But all patients with metastatic breast cancer and 40 percent of patients with... Read more »
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