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Sunday, October, 25, 2009

Tamoxifen Side Effects

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Tamoxifen Breakdown Gene CYP2D6 - Is the Plot Thickening?

By Kevin Knopf, MD Health Expert

I wrote about CYP2D6, which refers to a gene that codes for a biologic molecule involved in the breakdown of tamoxifen, about a year ago.  Since then it has not become standard of care to order this on patients taking tamoxifen, but my desire to do so has increased.  Routine testing is not yet recommended, according to those in the know.

 

We refer to women who have two normal copies of this gene as having the "wild-type," which means normal type for the breakdown of tamoxifen.  "Heterozygou...

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Tamoxifen (Nolvadex) and Fareston FAQs: Hormone Therapies to Prevent Breast Cancer Recurrence
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...tamoxifen, works in a similar fashion and has similar side effects, with one exception: it... Read more »

Health Guide

Types of Breast Cancer: Lobular Carcinoma In Situ (LCIS)
...years beyond when the woman stops taking it. As with any drug, tamoxifen carries its own possible side effects, so those need to be weighed against the risk of cancer.Q. I’ve heard of a friend... Read more »
Types of Breast Cancer: Ductal Carcinoma In Situ (DCIS)
...work, and having to put their lives on hold for awhile. Finally, if you take tamoxifen, expect few side effects other than a possible propensity to gain weight. Some women find themselves prone to... Read more »
Chemotherapy 101 Part III: Surviving Chemotherapy
Part III: Surviving Chemotherapy The Short and Long Of It Short-term side effects will subside after the last chemo dose – your hair will grow back (although be prepared for change – I went from... Read more »
Breast Cancer Hormone Treatment: Tamoxifen, other SERMs, and Aromatase Inhibitors
...benefit. Comparisons between tamoxifen and other SERMs used for adjuvant therapy are underway.Side Effects. Hormone therapy with SERMs has fewer side effects than chemotherapy, but can still cause... Read more »
Breast Cancer: Lifestyle Changes
...this is controversial. (Chemicals in green tea in particular have been studied for cancer-fighting effects in breast cancer.)Lycopene, found in tomatoes may have cancer-fighting properties. Click... Read more »

Medications

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Tamoxifen is used to treat breast cancer that has spread to other parts of the body (metastatic... Read more »

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...taking tamoxifen are greater than the risks of side effects. Seek immediate medical attention if... Read more »

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...periodically to monitor your progress or check for side effects. Consult your doctor for more... Read more »

Rox48340_146220_5

Tamoxifen is used to treat breast cancer that has spread to other parts of the body (metastatic... Read more »

Rox48340_146220_5

...taking tamoxifen are greater than the risks of side effects. Seek immediate medical attention if... Read more »

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