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Saturday, October 11, 2008

Breast Tissue Markers Help Predict Cancer's Course

(Page 2)

Here, the researchers analyzed DNA from the epithelium (membrane tissue) and stroma of 220 breast cancer tumors.

They found eight genetic markers on seven chromosomes within the stroma that were associated with differences in features of the tumors, including the grade of the cancer and how likely it was to have spread to the lymph nodes.

By contrast, only one chromosomal region in the epithelium had any similar associations.

Getting these findings into doctors' offices to help patients is a long way off, however.

"The next step is to replicate the findings in an independent series," Eng said.

More information

For more information on breast cancer, visit the American Cancer Society.

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