crestor and memory loss, behavioural change, change in taste

daughter Community Member March 22, 2008
  • My Mother was diagnosed with high cholesterol approximately 1 year ago.  She was not overweight, exercised regularly, and had a healthy diet compared to most North Americans.  She elected to try to improve her diet and exercise further before using cholesterol lowering drugs.  This Fall, her cholesterol was even higher, and with reluctance, she started on Crestor.  Within the last 3 weeks, she is suffering from short term memory loss.  She doesn't know what day it is, she puts her keys in my Father's coat pocket and then is upset because she can't find them.  To talk with her in a short visit, no one would know, but a longer visit makes it obvious.  She knows she cannot remember things, and it frustrates her.  Initially, she thought is was the Crestor, so after consulting some contacts we had in the health care profession, we have taken her off of this, and maintained her on Aspirin, until we can go to her doctor.  My Father took her to emergency, and they did a CT scan the following day which showed no abnormalities.  We will follow up with her attending doctor on Monday.    In searching the internet, I noticed postings of other behavioural changes as well as changes in taste being associated with statin drugs.  My mother experienced both of these, and at first I thought that this increased the likelihood that perhaps this was a drug reaction BUT then I realized she was NOT on the drug when she started having those problems.  I am thinking now that there is a higher possibility that she is having transient ischemic attacks ("mini strokes"), and so we need to rule that out.  We are so fortunate in Canada that we can do the required tests without an added financial burden weighing in to that decision.  

    My question is: In the reports of memory loss, how long were the patients off the statins before their memory returned? 

18 Comments
  • millie
    Apr. 11, 2012

    I have been taking crestor for the last couple of years and I too have been experiencing memory loss. I keep thinking I am developing early onset of Alzheimers or something. It is very frustrating because my husband will talk about things we have done or places we went and say "remember when??" and I do not remember at all. Some things from long ago I can remember...

    RHMLucky777

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    I have been taking crestor for the last couple of years and I too have been experiencing memory loss. I keep thinking I am developing early onset of Alzheimers or something. It is very frustrating because my husband will talk about things we have done or places we went and say "remember when??" and I do not remember at all. Some things from long ago I can remember and most common everyday repetitive things but many many memories just gone. I did stop taking it for about three months and did see some improvement but I am afraid to not take anything as my cholesterol is very high even though I am of normal weight and good health otherwise. I have lately been feeling some pressure on one side of my head and am paranoid I may be going to have a stroke. I am only 46. I may go back to my doctor after reading these posts. Thanks for the input. 

  • Anonymous
    yoly
    May. 18, 2009

    I read about the effects of statin drugs to memory loss and muscle pain.  I called up my mom's cardio and neuro.  They don't agree, in fact they think it enhances her memory.  I am stopping her crestor against there advise. Now she remembers the name of my children.  It's just been a week since I instructed her caregiver to stop.  Should...

    RHMLucky777

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    I read about the effects of statin drugs to memory loss and muscle pain.  I called up my mom's cardio and neuro.  They don't agree, in fact they think it enhances her memory.  I am stopping her crestor against there advise. Now she remembers the name of my children.  It's just been a week since I instructed her caregiver to stop.  Should I give her aspirin? My mom is just 77 years old and I noticed her unusual memory loss  3 years ago.  I noticed she forgets recent events.  Her long term memory is okey. She is taking Abixa drug once a day.  I a convinced it is her crestor that is causing this.  Maybe she is part of the 2% affected by the statin drug.  I don;t know. Appreciate any comment on this. I hope my guess is right. I am trying to convince my brothers and sister.thanks

    • Anonymous
      Anita R.
      Jun. 16, 2009

      My Mom started taking Crestor about 2months ago.  She was fine until she started taking this medicine.  Now she has short term memory loss can not remeber the day of the week, appts, and she can not take any of her meds without supervision. She is depressed and no longer does things that she enjoyed before she took the Crestor.  She can not sleep...

      RHMLucky777

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      My Mom started taking Crestor about 2months ago.  She was fine until she started taking this medicine.  Now she has short term memory loss can not remeber the day of the week, appts, and she can not take any of her meds without supervision. She is depressed and no longer does things that she enjoyed before she took the Crestor.  She can not sleep at night, and has panic attacks.  We questioned the doctor who said that she is depressed and prescribed Zoloft. It has been over 2 weeks since she is on Zoloft and there is no change in her forgetfulness.  If I take her off this medicine will the memory loss be reversed?  I truly believe the Crestor has caused this decline in her memory and her behavior. Please send  your comments. I am so worried.

    • Anonymous
      yoly
      Jun. 17, 2009

      Yes it's been a month since my mom stopped her crestor. I had her complete blood test done. and all is normal including her cholesterol level. I ve been calling her regularly to check on some small details to check on her memory ( good memory about 10% improvement). I suggest you consult her doctor to  changing your anti depressant . Lexapro worked well...

      RHMLucky777

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      Yes it's been a month since my mom stopped her crestor. I had her complete blood test done. and all is normal including her cholesterol level. I ve been calling her regularly to check on some small details to check on her memory ( good memory about 10% improvement). I suggest you consult her doctor to  changing your anti depressant . Lexapro worked well with her.

    • Anonymous
      yoly
      Jul. 22, 2009

      Dear anita,

       

      I notice my mom's memory lapses in 2006. He was given anti depressant because of a change in her moods. Since the time I stopped her crestor against her cardio and neuro docs advise, her moods are okey. Her short term memory is still a problem but her cholesterol is normal.  Her long term memory is not that bad. She still remembers us. ...

      RHMLucky777

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      Dear anita,

       

      I notice my mom's memory lapses in 2006. He was given anti depressant because of a change in her moods. Since the time I stopped her crestor against her cardio and neuro docs advise, her moods are okey. Her short term memory is still a problem but her cholesterol is normal.  Her long term memory is not that bad. She still remembers us.  I still believe the culprit is crestor and all the statin drugs.  They say only 2% of population taking statin drugs are affected.  Well, they belong to the 2% I guess.  she's been taking crestor for the last 6 years. Good luck let us keep in touch

    • Cheryl
      Dec. 09, 2010

      RE: CRESTOR

       

      My doctor changed me from Pravachol 80 mg to Crestor because of muscle pain I was having.  After the seventh day of taking Crestor I have started having panic attacks...even waking up at night with them.  I have been feeling confused and having nausea.  I stopped taking the medicine and within 3 days I am feeling almost normal...

      RHMLucky777

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      RE: CRESTOR

       

      My doctor changed me from Pravachol 80 mg to Crestor because of muscle pain I was having.  After the seventh day of taking Crestor I have started having panic attacks...even waking up at night with them.  I have been feeling confused and having nausea.  I stopped taking the medicine and within 3 days I am feeling almost normal again!

    • Jerry
      Jul. 23, 2011
      I had heart attack 2007 and surgery saved my life..after taking lipitor for the years after surgery, the doc switched me to crest or....I was having nausea and panic attacks with lipitor..it is worse now with crest or......I suspect it's these statins because my doc kept me off them totally in between switching.....then once I started taking crest or it started...
      RHMLucky777
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      I had heart attack 2007 and surgery saved my life..after taking lipitor for the years after surgery, the doc switched me to crest or....I was having nausea and panic attacks with lipitor..it is worse now with crest or......I suspect it's these statins because my doc kept me off them totally in between switching.....then once I started taking crest or it started all over again...the doctor does not really have answers.....but I am tired of thinking I am having another heart attack because of these statins...I am looking into other therapies to keep things in check......these attacks send me to the er sometimes..that's how bad they are....one time my cardio doc was in the er doing the rounds and I was there having a doozy of an attack.....glad he was there...I was not having heart attack, but at least my doc could finally see what I was trying to explain what happens to me.....it makes you crazy.....I do not want to be like this.....it's a viscous cycle that I hope to get off.......
    • Anonymous
      Anonymous
      Jul. 20, 2009

      Keep away from Lipitor and Crestor...  Most people who do not have side effects either have no muscle to get affected or are totally forgetfull anyway. If you have any muscle or half a brain, do not take the stuff !!!!!!!!!!!!!

    • stent patient
      Apr. 17, 2010

      I am on Crestor 10mg for a month now, I noticed short term memory loss after about 2 weeks on the medication.  This morning, I went to the golf driving range and tested some clubs, when the sales person asked me what clubs I was using, I just had a blank.  Now, I play golf all the time and raved about my clubs and the brand.  For the last two...

      RHMLucky777

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      I am on Crestor 10mg for a month now, I noticed short term memory loss after about 2 weeks on the medication.  This morning, I went to the golf driving range and tested some clubs, when the sales person asked me what clubs I was using, I just had a blank.  Now, I play golf all the time and raved about my clubs and the brand.  For the last two weeks, I lost keys, could remember colleagues and client's names (I dont have this problem), I could remember names and models of the sound system equipment that I am retailing.   I am really worried, on one hand I need to lower my cholesterol, on another, i cannot bear this short term memory loss..

    • Anonymous
      MSI
      Aug. 04, 2010

      I have been taking Crestor for about 5 years or more and I have noticed short term memory loss over the years. My wife has been joking for few years that I have Alzheimer's but we actually thought that it is part of aging process and stress.

       

      Recently, I noticed that my forgetfulness is in fact causing stress. I cannot remember within few seconds if I...

      RHMLucky777

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      I have been taking Crestor for about 5 years or more and I have noticed short term memory loss over the years. My wife has been joking for few years that I have Alzheimer's but we actually thought that it is part of aging process and stress.

       

      Recently, I noticed that my forgetfulness is in fact causing stress. I cannot remember within few seconds if I locked the car or if I took my daily pill of Crestor. I have difficulty in remembering the names, reading a telephone number and dialing it. I can give you many examples.

       

      Today, I stumbled across relationship between Crestor and Memory loss while checking reviews for "Focus Factor".  I do not take any other medication.  My cholesterol is on borderline and due to my frequent job related travels, I do not have much control on what I eat.

       

      Starting today, I will stop taking Crestor and will update after few weeks if my short term memory improves.

       

      Let's see!

    • Anonymous
      debbie
      Sep. 22, 2013

      any update on memory and Crestor sessation?

       

  • Sue
    Sue
    Mar. 24, 2008

    Hello and thanks for your post.  I am the moderator for the site and though not medically trained I can try and help find answers to your questions.

     

    I searched our site and was able to find some information regadring Crestor.  It is described as:

     

    Rosuvastatin is an enzyme blocker (HMG-CoA reductase inhibitor), also known as a "statin."...

    RHMLucky777

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    Hello and thanks for your post.  I am the moderator for the site and though not medically trained I can try and help find answers to your questions.

     

    I searched our site and was able to find some information regadring Crestor.  It is described as:

     

    Rosuvastatin is an enzyme blocker (HMG-CoA reductase inhibitor), also known as a "statin." It is used along with a proper diet to help lower fats (triglycerides) and cholesterol in the blood. This drug is usually prescribed after non-drug treatment options have not been fully successful at lowering cholesterol (e.g., diet change, increase in exercise, weight loss if overweight). Reducing cholesterol and triglycerides help prevent strokes and heart attacks.

     

    Although I was not able to find details on memory loss with Crestar specifically, I was able to find something on Lipitor and memory loss.  And as Lipitor and Crestor are members of the same group of statins, I thought this might be of interest to you.

     

    If anyone has any experience with this - please join the discussion.  This is a great way for you to help others and get involved in our community. 

     

    Hope this helps - look forward to hearing from you soon.

     

    All the best, sue 

    • daughter
      Mar. 25, 2008

      Thanks Sue,

       

      A few things I have found out since; There was a review article published that I think I originally found on your site entitled Statin-associated memroy loss: an analysis of 60 case reports and review of the literature.  I only have an abstract, so I am asking my husband to locate the full text.  Since my posting, my mother has had...

      RHMLucky777

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      Thanks Sue,

       

      A few things I have found out since; There was a review article published that I think I originally found on your site entitled Statin-associated memroy loss: an analysis of 60 case reports and review of the literature.  I only have an abstract, so I am asking my husband to locate the full text.  Since my posting, my mother has had another CT scan, bloodwork, seen her doctor, been referred to and examined by a neurologist (so I can't at all say that the probelm is being ignored!)  All of the testing has not revealed any abnormalities.  The neurologist is 99% certain this is not a stroke.  He thinks that she is so worried about side effects of the Crestor that she cannot concentrate on anything else.  This, according to my father.  My father said that after a 10 minute conversation about cholesterol that she is back to normal and the nerologist convinced her to go back on the Crestor.  I find this very hard to believe.  When I saw her yesterday, she forgot that I was there for supper the day before, she didn't know what day it was, and she kept saying that she couldn't remember anything. anyhow, I will keep you "posted".

       

      Thanks again. 

    • Anonymous
      Joan Bond
      Apr. 21, 2008

      I was diagnosed a couple of weeks ago with high cholesterol and my doctor prescribed Crestor.  I read everything I could about it and let the doctor know that I was opposed to taking this drug because of the side effects one being memory loss.  I had a small stroke about 3 years ago and the neurologist prescribed a medication that honestly I can't...

      RHMLucky777

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      I was diagnosed a couple of weeks ago with high cholesterol and my doctor prescribed Crestor.  I read everything I could about it and let the doctor know that I was opposed to taking this drug because of the side effects one being memory loss.  I had a small stroke about 3 years ago and the neurologist prescribed a medication that honestly I can't remember the name (memory loss) but I explained my hesitancy against that drug also because of the side effects.  I asked him could I take aspirin and he agreed to this.  I took a low dose of aspirin off and on for a year or so and finally gave that up. I have been taking Crestor for a week now, against my better wishes, and I noticed today a loss of memory that was embarrasing.  I had a call from a person I know, but for the life of me could not remember who she was.  When I finally realized something I told her in our conversation, I called her back and apologized and let her know that I couldn't remember who she was until our call was complete.  I think at this point I am going to call the Dr. and let him know I am not willing to risk my memory to a drug this scary.  Hope your Mom is OK.  Joan 

    • Anonymous
      Verona
      Feb. 28, 2009

      My husband started taking Crestor about a month ago and his "quick thought" memory seems to be affected.  For example, tonight he was trying to say something about the broccoli we were having for dinner and he couldn't think of the name.  He kept calling it brussel sprouts and knew it was the wrong name.  He's been doing that sort of thing int...

      RHMLucky777

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      My husband started taking Crestor about a month ago and his "quick thought" memory seems to be affected.  For example, tonight he was trying to say something about the broccoli we were having for dinner and he couldn't think of the name.  He kept calling it brussel sprouts and knew it was the wrong name.  He's been doing that sort of thing int he last few days, and I've been wondering if it could be from the Crestor.  I'll keep an eye on things and mention it to his doctor if it continues.  But after reading messages on the internet, I'm pretty well convinced that there is a connection.

    • Anonymous
      Michael in NJ
      Apr. 21, 2009

      I was taking Zocor, which is a statin relative of Crestor, and I developed the same memory loss side effect. There is a hiostory of dementia in my family, so I was terrified that I was losing my mental faculties at 53 years of age. I expressed these fears to my MD, and she said that she had experienced the same problems...her cardiologist took her off the Zocor...

      RHMLucky777

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      I was taking Zocor, which is a statin relative of Crestor, and I developed the same memory loss side effect. There is a hiostory of dementia in my family, so I was terrified that I was losing my mental faculties at 53 years of age. I expressed these fears to my MD, and she said that she had experienced the same problems...her cardiologist took her off the Zocor immediately. I now use cholestyramine and it works well.

    • Anonymous
      Anonymous
      Apr. 25, 2009

      My Mom and Aunt just went through this.  My Aunt took Lipitor and my Mom took Crestor.  Both experienced extreme muscle pain in thier knees, memory loss (losing days and conversations), depression, and the feeling of no energy.  They both went to thier Doctors repeatedly to question symptoms with no luck - but a lot of tests.  My mom was...

      RHMLucky777

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      My Mom and Aunt just went through this.  My Aunt took Lipitor and my Mom took Crestor.  Both experienced extreme muscle pain in thier knees, memory loss (losing days and conversations), depression, and the feeling of no energy.  They both went to thier Doctors repeatedly to question symptoms with no luck - but a lot of tests.  My mom was attributing her symptoms as feelings due to the recent passing of my Dad.  My Aunt went to a homeopath that said it was probably the Lipitor.  She got off it and started feeling better within a few weeks.  She called my Mom this weekend to tell us about this.  My mom has been taken off the meds at this time due to raised enzyme levels.  Memory loss is listed in the Crestor lit as being reported post clinical trials.  If you can remember - "call your doctor right away, as these symptoms could be a sign of a rare but serious side effect."  Hopefully your Doctor will connect your symptoms to the meds should you have them.  I've told a few people about this and it seems like this is not so rare of an occurance.

    • barbara goodman
      Aug. 06, 2013

      Yes I have noticed significant memory loss since I am on Crestor, I had no idea what was causing it till I saw this website.