One positive aspect from the ENHANCE study was that ezitimibe appears to be quite safe. There was no additional risk to liver or muscle when ezitimibe was given with a statin. At least ezetimibe is not physically hurting people, but financially it may be another story. A 1 month supply of Zetia or Vytorin costs ~$90 while a month's supply of generic simvastatin costs ~$30. I suppose we'll have to wait a little longer before we'll know if taking this medication is actually helping people other than the shareholders of Merck and Schering-Plough.

