Medication for persistently high triglycerides can be considered for high risk people or if the triglyceride level is very high (>500mg/dl), but caution must be used since some medicines such as fibric acid derivatives are associated with more side effects in the setting of kidney failure.
The problem with the above recommendations is that there is very little data specifically looking at the effects of cholesterol lowering therapy in people with chronic kidney disease. The first study published in 2005 did not show any benefit with statin therapy in people with chronic kidney disease but it did not show any harm either. There are 2 more large scale studies currently in progress designed to answer this question. Until then, cholesterol management in chronic kidney disease remains similar to that in heart disease.
Read more:
Triglycerides: One of the Most Important Numbers on Your Cholesterol Panel
What is Cholesterol: A Patient Guide
Why Average Cholesterol Values Can Be So Bad
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