An interesting article appeared in USA Today concerning the influence of pharmaceutical advertising on prescription practices by physicians. The survey performed by the Kaiser Family Foundation and the Harvard School of Public Health reported that prescription drug ads prompt nearly a third of Americans to ask their doctors about a specific... Read more
Our body's lipids such as triglycerides and cholesterol are insoluble in circulating plasma (the fluid component of our blood.) In order to carry around these lipids, we must package them with proteins to make them dissolve in plasma. These proteins are called apolipoproteins. Apolipoproteins + lipids together make up what is called a... Read more
"This is a pretty clear failure. Physicians should now stop using ezetimibe or Vytorin except as a last resort." - Dr. Steven Nissen (Cleveland Clinic, OH) "Dr. Nissen's suggestion about a moratorium on ezitimibe is rather alarmist, given that this was just an imaging study, and an imaging study should not change... Read more
In December 2007, the New York Times published an article entitled "Data about Zetia risk was not fully revealed." The article claimed that Merck and Schering-Plough, the manufacturers of Zetia (aka ezetimibe), have information pertaining to the risk of liver damage when taking this cholesterol lowering medication in... Read more
I have written several articles pertaining to a new class of cholesterol controlling medicines called CETP (cholesterol ester transfer protein) inhibitors. CETP inhibitors can markedly raise good HDL cholesterol and moderately lower bad LDL. Most recently, all my articles have been negative given that the most clinically tested drug of this... Read more
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