In the beginning of this year, I wrote two articles concerning torcetrapib, the $800 million failure of Pfizer to develop a new type of cholesterol medication. This novel medication called a CETP (cholesterol ester transfer protein) inhibitor is able to markedly raise HDL, but unfortunately was found to increase the risk of death. The... Read more
High cholesterol, specifically high LDL and low HDL, is clearly a risk factor for the development of heart disease, heart attack, and death. High cholesterol promotes the development of atherosclerosis or fatty plaques in the heart arteries. The blood flow to the heart muscle can then be slowly interrupted by this gradual narrowing or suddenly... Read more
Now that National Cholesterol Education Month has ended, I thought this would be a good time to highlight some of the recent accomplishments in cholesterol treatment during this past year. But it's only fair to also highlight some of our recent failures as well. Looking at both our successes and failures helps us to gain a perspective on... Read more
Most people think that if they are diagnosed with high cholesterol that a prescription medication is in their immediate future. This is not necessarily the case given that there are several non-pharmaceutical ways in which you can lower your cholesterol. Unfortunately, most people eventually end up on some type of drug therapy to achieve... Read more
It's quite commonly known that high total cholesterol and LDL levels are directly related to an increased risk of heart disease and that the relationship is graded and continuous. This risk even applies to people under the age of 40. Low HDL and high triglycerides also contribute to this risk but apparently to a lesser extent, especially... Read more