Thursday, October 23, 2014
Tuesday, June 16, 2009 Gregory Besaw, Community Member, asks

Q: Can I substitute Pravastatin 40 mg for Simvastatin 40 mg?

Can I substitute Pravastatin 40 mg for Simvastatin 40 mg?

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Answers (3)
6/17/09 12:59pm

Hi Gregory,


Consult your physician any time you want to change your medication.


All the best,

Lisa Nelson RD

How to Lower Cholesterol in 8 Simple Steps

thomas ross, Community Member
5/29/11 11:37pm
Can I substitute Pravastatin 40mg for Simvastatin 40mg? Reply
Jemi, Community Member
10/28/11 3:27pm

I substituted Pravastatin 40 mg for 20mg Simvastatin because of liver concerns and found it did not work for me. Had serious leg pains, cramps, muscle weakness and could not sleep with Pravastatin. Had to revert to Simavastatin after two weeks and will retest lipid panel in 90 days. HDL is 45, LDL 68, Trig 128, VLDL 26.

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By Gregory Besaw, Community Member— Last Modified: 12/31/12, First Published: 06/16/09