As mentioned in my previous article , non pharmacological treatment for high triglyceride (TG) levels can be quite effective with diet and exercise alone contributing to an almost 33% reduction. However, for some this may not be enough, and for others the effect may be too difficult to maintain over the long run. Medication to lower TG levels can be quite safe and effective, but they are always added on top of a background of a healthy diet, weight loss, and regular exercise. The indication to take medicine to reduce TG levels depends on your overall risk for a heart disease. If other significant risk factors exist such as history of a heart attack , high blood pressure , diabetes , strong family history, or artery disease in an extremity, then using medicine to achieve a target TG level of <150mg/dl may be warranted. High TG levels can also exist with other bad levels of cholesterol such as high LDLs and low HDLs. Since high LDL is a much stronger risk factor to heart ...
What is the best way to take my pills?
This question is at the root of more confusion than any other question in medicine. The public wonders about which pill is best for a given disease, and we are constantly under the barrage of pharmaceutical advertising, but the fact still remains that most doctor's prescriptions are not filled. And even when the prescriptions are filled, they are rarely taken as directed. Whose fault: we all share equally, doctor, pharmacist and patient. This is not good, since we are all trying to work together.
I saw a cartoon in a magazine once on this subject. The doctor told the patient "take one pill twice a day". The patient looked confused and then asked " Doc, don't I swallow it the first time?"
One of my sons collected labels from the pharmacy and kept them on a prescription bottle. The instructions were actually comical when viewed from the right perspective. "Do not swallow". "For rectal use only." "Use as directed". "To be put in left ...
The JUPITER study has been the subject of countless headlines reporting the unprecedented reduction in heart attacks with the cholesterol drug, Crestor® . The study has received gushing pronouncements of the inestimable value of statins by my cardiology colleagues.
Pharmaceutical giant, AstraZeneca, sponsored this study of nearly 18,000 people (men 50 years and over, women 60 years and over). Participants took 20 mg per day Crestor or placebo for two years.
The premise being explored was whether a cholesterol drug like Crestor® yields any benefit in people without high cholesterol but with a high measure of the body's inflammatory state, c-reactive protein, or CRP. Participants therefore were selected to have starting LDL cholesterols in the "normal" range of no higher than 130 mg/dl and elevated CRP of 2 mg/dl or greater.
Crestor® treatment resulted in 44% reduction in nonfatal heart attack, nonfatal stroke, hospitalization for unstable angina, revascu...
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