Saturday, October 25, 2014
Sunday, October 12, 2008 carolyn dalton, Community Member, asks

Q: what are side efftects of Simvastatin 20 mg tab

What are the common side effects of simvastatin 20 or 40 mg?

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Answers (16)
Martin Cane, M.D., Health Pro
10/13/08 3:39pm

carolyn dalton,


Thanks for your question.   Simvastatin is a medication used in the treatment of elevated fats (lipids) in the blood.  It lowers total cholesterol, and specifically lowers "bad cholesterol" (LDL) and raises "good cholesterol" (HDL). 


I am inserting the side effect section for simvastatin from our website:



      Side Effects

            Stomach upset may occur. If this effect persists or worsens, notify your

            doctor or pharmacist promptly.


            Remember that your doctor has prescribed this medication because the

            benefit to you is greater than the risk of side effects. Many people using this

            medication do not have serious side effects.


            This drug may infrequently cause muscle pain, tenderness, or weakness

            (which can rarely lead to a very serious condition called rhabdomyolysis).

            Seek immediate medical attention if you develop these muscle problems 

            (especially with fever or unusual    tiredness).


            Tell your doctor immediately if any of these highly unlikely but very serious

            side effects occur:

  • yellowing eyes and skin
  • dark urine
  • severe fatigue
  • stomach/abdominal pain
  • persistent nausea
  • change in the amount of urine

            A serious allergic reaction to this drug is unlikely, but seek immediate medical

            attention if it occurs. Symptoms of a serious allergic reaction include:

  • rash
  • itching
  • swelling
  • dizziness
  • trouble breathing

            If you notice other effects not listed above, contact your doctor or




Our website has much more information about simvastatin.  Just go to the search portion of this page and type in the medication name and press search.  Be sure to review this website for more information and tips on getting your lipids down, including diet, exercise and lifestyle changes. 


I hope this has been helpful.


Martin Cane, M.D.


P Chacon, Community Member
12/ 6/09 8:57pm

I just started taking this medication and immediately I am having pain in my right inner thigh area causing me trouble walking upon rising in the morning. It goes away but does come and go later in the day.

lawmed, Community Member
11/ 4/10 10:51am

STOP THE DRUH IMMEDIATELY AND TALK WITH YOUR DOCTOR. There is absolutely no harm in stopping a statin cold turkey. You are having a potentially serious known side effect of these drugs and it MUST be discontinued.

neta, Community Member
1/ 8/11 9:17pm

I am having the same problems I start taking the simvaststin for 3 months then I hurt my back exercising and I had muscule spasm for a week and then elevate to my legs my back is better but my legs are very week is hard to walk and the

dr think i have PAD so I had tested for both PAD and PVD and are both normal I'm having the same symtem as you having trouble walking upon rising in the mornig.

dustty, Community Member
5/ 5/11 3:46pm

I have been tacking simastatin for about 4 months I have pain in my right hip that comes and goes now all my joints hurt and my muscles

Von, Community Member
1/19/11 2:21pm

My mother has been taking Simvasatatin 20mg for nearly 3 yrs, she had a heart attack 10 years ago and also s stroke. The last 2 years she has been complaining of 'feeling not with it' in her head, Dizzyness / cotton wool feeling. And she finds it difficult to walk long distances. Before thaking the tablets she was a very healthy 70 year old woman. Shall i advise her to stop taking for a couple of weeks and see if she feels better>

Beverly, Community Member
3/17/12 7:13am

Hi i was on silvastatin for 9yrs have been really unwell the last 5 weeks terrible muscle pain some mornings i cannot get out of bed bouts of severe cold teeth chattering unable to warm myself and then i have a raging temp dark urine and constapation i visited the doc they tested for arthritus and thyroid but everything fine so seen doc again and he advised me to stop silverstatin as i have lost 6 stone in weight and do not need them anymore however i have been off them for 2 weeks still really unwell aparently they can take up to 6 mths to get out of my system feeling really sorry for myself at the mo xx

marlene, Community Member
4/10/12 6:09pm

thank you for the info its been helpful. my cholesterol is 233 is that very high should i really be on this

Lanny, Community Member
8/14/12 9:17am

Im a 63 yr old male with crohns disease..Ive been taking simvastatin for approx 4 yrs, I just stopped taking it, its been about 4 days now and Ive NOTICED an improvement in my crohns God what a relief for me...I hope it continues.

Lanny, Community Member
8/14/12 9:18am

Im a 63 yr old male with crohns disease..Ive been taking simvastatin for approx 4 yrs, I just stopped taking it, its been about 4 days now and Ive NOTICED an improvement in my crohns God what a relief for me...I hope it continues.

Lanny, Community Member
8/14/12 9:18am

Im a 63 yr old male with crohns disease..Ive been taking simvastatin for approx 4 yrs, I just stopped taking it, its been about 4 days now and Ive NOTICED an improvement in my crohns God what a relief for me...I hope it continues.

Lanny, Community Member
8/14/12 9:18am

Im a 63 yr old male with crohns disease..Ive been taking simvastatin for approx 4 yrs, I just stopped taking it, its been about 4 days now and Ive NOTICED an improvement in my crohns God what a relief for me...I hope it continues.

ginny, Community Member
9/23/09 9:04pm

why should i take it at bedtime

ginny, Community Member
9/23/09 9:05pm

why should i take it at bedtime

beechick, Community Member
10/ 1/09 10:28am

my dr from the u of m told me the reason you take it at night is because that is when the bad cholesterol remakes more and this slowes it down, and that is why you have to have a blood test 2 weeks after starting to make sure you are still making enough and why you need testing regular...does it make me want to start using it NO but what else is a person to scares the hell out of me putting something else man made in my i stare at my first new bottle....

trillium, Community Member
10/26/09 6:43pm

Me too. Im looking at the posible side effects, and my doctor said it may cause muscle pain, but not likely. And no grapefruit juice...? What is that about. I too do not like the idea of changing blood chemistry around, but the alterative is worse I suppose. Wonder if ther are thosee out there who have indeed had side effects?


flanigan, Community Member
11/ 2/09 3:46pm

It causes me muscles pain. I wonder  if I should  stop taking it. My Chol level is low now. TOTAL is  only 87.

HDC  is 37.

lLDCs 107.  


KEEPING HEALTHY, Community Member
12/ 3/10 9:31pm


carol, Community Member
1/ 4/11 6:31pm

I  tryed it at bed time. I could,nt sleep at night.  I start taking it in the afternoon after lunch. It worked for me. Yes why take it at bed time?.


Poochie, Community Member
12/14/09 3:13pm

I am currently taking 1/2 tablets of 10mg Crestor, at my doctors request. The 10mg was too much he thought.  I am changing to Simvastatin.  He prescribed 20mg.  Is this equivalent?  Or, where can you go to see what mg's are equivalent of two different durgs.   Thanks.

Tom Grant, Community Member
3/25/10 7:28pm

Does Simvastation 20 mg cause a change in my metabolism, cause a gain in weight?

yenna, Community Member
11/ 4/10 1:12am

yes it makes your belly swell up I have been on these Tabs for the past mth and was a size 10 now am a  size 12 and its awful so I am now  on Lipator the new one that has just been given a free clearance ,I think I feel  likeI am Bio Imbalance

shirley, Community Member
4/27/10 1:11pm


cordel, Community Member
5/14/10 12:59pm

What is simvastatin usually substituted for?


Shirley, Community Member
6/26/10 1:05am

My insurance company doesn't want to pay for the high cost of Lipitor.  So,my doctor substituted Simvastatin 20 mg.  The ban on generic Lipitor runs out Nov. 2011, I understand.  I took Lipitor for 5 years before changing to Simvastatin.  I haven't had any side effects.

yenna, Community Member
11/ 4/10 1:15am

Newzealand has just let the Lipitor be subbed so thats a plus

the bowler, Community Member
2/17/12 11:07pm

I have been on Simvistatin/Zocor 20 for about 15 years and have no known side effects.   I stop taking it when I have Grapefruit.  I do not understand why though. 

lYNNE, Community Member
8/ 7/10 11:03am

What about hair loss while taking  Simvastatin. I seem to be loosing my hair.

Thanks  Lynne

yenna, Community Member
11/ 4/10 1:18am

I am a Hairdresser and found that Lipex had that side effect but the Simvastatin did not have that effect

lawmed, Community Member
11/ 4/10 10:49am

Ugh...there is not enough room here, nor is this the right forum for me to go on about the utterly flawed science behind the cholesterol myth and the big pharma statin fraud. Suffice it to say...if you have having ANY muscle pain from these drugs STOP THEM IMMEDIATELY. If you, or a relative, beginto have neurologic or mental impairment including depression, "dementia", alzheimer like symptoms, confusion, memory loss, ANY cognition issues...STOP THE DRUG IMMEDIATELY.


If you are over 70, lowering your cholesterol may very well kill you. DO NOT TAKE A STATIN. If you are under 40 and someone wants you to take a statin ASK THEM WHAT LONG TERM EFFECTS CAN BE EXPECTED ON YOUR BRAIN AND FOR RESEARCH WHICH BACKS UP THEIR "OH THAT'S NOT A PROBLEM" RESPONSE. I


If you are anyone else...DO YOUR HOMEWORK BEFORE YOU AGREE TO TAKE A STATIN...I HAVE GIVEN ANESTHESIA FOR 20 YEARS AND I WOULD NOT TOUCH A STAIN WITH A 10 FOOT POLE. NOR DO I ALLOW MY FAMILY TO TAKE THEM. This is CRAP science and a multibillion dollar fraud...that CAN leave you a blubbering idiot, or kill you.

Pepper, Community Member
12/14/10 10:29am

Can you tell me more please?  I am just turning 70 and my cardio doc just yesterday prescribed 20mg of simvastatin.  I have yet to fill it due to all I have read about the side effects.  Your posting is most vivid.  I lead a very active life style, walking 60 minutes daily, lifting weights, avoiding stress and carefully monitoring my diet.  Still, my levels are all high.  The doc says my body makes cholesterol.  I do not know what more I can do to avoid a medical problem in this regard.  My e-mail address is:  Any further advice you can give me would be most welcome.  I do not want to be a walking statistic, and I really feel good right now.  Taking this medicine might just throw me way out of balance.  Thank you for your attention to my inquiry.  

jdb, Community Member
1/ 9/12 9:43am

Please give references of research that substantiates your comment

MCONCORDIA, Community Member
12/ 2/10 8:11am

My doctor allowed my prescription plan to change from Lipitor 10 mg to SIMVASTATIN 20MG, is that OK?

orlando, Community Member
5/28/11 10:55am

side form simvastatin and glipizide and metformin.

Barbara Risi, Community Member
6/15/11 8:39pm

I have been taking 20 mg for three weeks and have tenderness in the calf of one leg. Should I be concerned. I am also very tired. I am also taking medication for hypothyroidism.

janetsue, Community Member
10/25/11 12:52pm

Does Simvastatin cause heartburn

nancy, Community Member
12/26/11 8:50pm

does it cause you to have burst of crying?

aca, Community Member
1/12/12 1:31am

i hv just started this medication since three day and now my viginal came out white discharge and it is very itch? do i need to proceed taking this medication or seek for doctor advice?

Liz, Community Member
5/ 7/12 4:14pm

i do not get into a deep sleep when i take 20 mg of i have to take at night ?

ljw, Community Member
3/14/13 8:56pm

The heel of my left foot is very sore it's hard for to walk normal sometimes.the pain comes and goes .it hurts mostly when I sit or ride vthen get up to walk. Cannot walk fast .Have anyone encounterd this?


emz, Community Member
3/14/14 10:14pm

Hi, my doctor prescribed me simvastatin for 1 month after my lab result  to lower my slight bad cholesterol.I have been taking simvastatin 20mg for 10days now but it disturbed my period making it delay from its regular cycle. I wonder if it is one of the side effects because it is not among those listed side effects?My activities are the same and im not having intimate relationship. Thank you

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By carolyn dalton, Community Member— Last Modified: 08/15/14, First Published: 10/12/08