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Q: Why is it recommended that you take Simvastatin in the evening?
SkyeFllion,
Thanks for your question. Simvastatin is the generic for Zocor, one of the stronger statin medications available for the treatment of elevated cholestrol levels. Most statin medications are recommended to be taken in the evening, though Crestor (another statin) can be taken at any time of day.
Apparently, the drug half-life (how long it lasts in your body) is a factor in determining this. One study monitored LDL (low density lipoprotein levels of Cholesterol) following doses of statin medications. Lower levels of LDL were observed when these medications were taken in the evening rather than the morning.
Please review our website for tips and suggestions for keeping your cholesterol under control (in addition to your medication).
Best wishes.
Martin Cane, M.D.
The answer is that, more of the body's cholesterol is formed during the night, so taking the statin in the evening allows it to work all night on the new cholesterol being formed9in the liver), thus helping to maintain/lower your cholesterol levels.
half life plys a role too, but the main ting is the production/ removal of cholesterol from the night.
I am also interested in this topic.
I don't know
It works better after you have eaten your last meal for the day. The food is breaking down so it is easier for the medicine to work.
IT IS MORE EFFECTIVE AFTER FOOD HAS BEEN CONSUMED DURING THE DAY
Why do we have to take simvastatin in the evening? My doctor did not tell me this
full stomach
It works better at night when the stomach isn't full and the body is resting.
It was recommended that I take Simvastatin in the evening because this pill works on the liver. It works better at bedtime when taken after or during dinner.
Cholesterol and LDL synthesis is greatest during the fasting period early in the morning. This coincides with the greatest activity is simnvistatin in the body since the half-life of simvistatin is ~5 hours. If taken at any other time of the day, the concentration of simvistatin would be lower during the time of high cholesterol synthesis.
it is supposed to be effective
because you eat during the day, but not at night when you a sleep
This is ~SkyeFlion~
Thanks for all your answers, some of which bring me to another question:
I generally take all of my pills at about 7:00 AM. I start my workday day with a SlimFast at about 8:15 AM. I then drink about a half gallon of water before my 1:00 PM lunch break. This means my stomach is empty when I take the Simvastatin and pretty much stays that way through the morning except for the above. I hope you can tell me this will work as well as taking it in the evening. I do not have any other pill to take in the evening and am worried I will be constantly forgetting this if I have to switch to the evening for this one medication.
surely in todays technological world you have a cell phone that has a reminder setting?? this is what my husband and I do to remember to take our morning and evening medication. after a few weeks a habit will be formed and you will be turning off that reminder before it even goes off.
So it has time to work through your system.
I belive other than sometimes make you alittle sick,it also has been known to make you dizzy and sleepy.So as you sleep you won't notice these.
Cholesterol is absorbed in the evening when you sleep.
works better
Becuase it raises your blood pressure?
The metabolism of cholesterol in our body is not the same at night, it must be more active at this time ?
i do not know
My Husband's Cardiologist advised him to take his Zocor in the evening after his meal. This way the drug stays in your system longer due to a full stomach. Also it lessens the possible side affect of nausea.
would it be reasonable for zocor to reduce my ldl from 154 to 87 and triglycerides from 169 to 66 by 19 days after starting simvistatin?
nineteen days after starting simvistatin my ldl's went from 154 to 87 and my triglycerides from 169 to 66. is this reasonable progress?
Can simvastatin be taken with food or needs to be taken with a empty stomach.
The Liver creates new lipids and fills them with fat for distribution much more when you sleep than when you are awake. This is why, when you read the drug companies leaflet, it says AT NIGHT. Some statins don't require night time consumption because they work in a slightly different way.
Just to add, it makes no difference whatsoever if you take them on a full stomach or not. This medication is aimed at the Liver, not the digestive system. Medications such as Ezetimibe will affect the gut, by reducing the amount of fat absorbed.
Around 20-25% of fat in the Liver comes from the food we eat, the rest is made by the Liver. This is why people with Familial Hypercholesterolemia for example have cholesterol levels through the roof even if they live on salads.
Well now I am really confused, I asked the pharmacist and he suggested |I take it in the evening, which I have tried this week, but when i take my blood pressure medication in the morning, I feel rather 'yuk' and lifeless for a couple of hours. There are also ''personal' side effects in the morning.
So think its a trip back to the docs for me, or maybe just revert to taking Simvastatin just after my evening meal.
Well now I am really confused, I asked the pharmacist and he suggested |I take it in the evening, which I have tried this week, but when i take my blood pressure medication in the morning, I feel rather 'yuk' and lifeless for a couple of hours. There are also ''personal' side effects in the morning.
So think its a trip back to the docs for me, or maybe just revert to taking Simvastatin just after my evening meal.
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I work 9 PM to 7 AM for 7 nights in a row and then off 7 where I turn around and sleep during the night. So, when should I take Zocor? Thanks