Saturday, October 25, 2014
Friday, June 13, 2008 Barb, Community Member, asks

Q: do statins cause leg and feet cramps

When I take cholesterol drugs with or without statins, I get 20 to 40 leg cramps or cramps in my feet mostly at night while in bed.  Sometimes I get them just sitting.  I used to stop taking them for a week or two and the cramps would be gone.  The last time I quit taking them was about a year ago and it has taken until now for the cramps to mostly subside.  The drs. insist my cramps aren't from the cholesterol drugs but I could swear they are.  Does anyone else have this problem?  Thank you for your input.

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Answers (117)
Daniel Marquez, Community Member
6/24/08 4:26pm

The answer is yes, in my opinion.  Sealed Statin drugs (such as Zocor, Lipitor, Lovastatin, Pravachol, Mevacor, and Lescol) may cause cramps and other forms of myopathy because they block cholesterol production in the body by inhibiting the enzyme called HMG-CoA reductase. (Please see the "mevalonate pathway" for details.) Unfortunately, the antioxidant CoQ10 is also synthesized from another HMG-CoA reductase pathway.  Therefore, statin drugs also inhibit CoQ10 (Coenzyme Q10) synthesis. Low levels of CoQ10 could predispose the patients to cramps, including cramping in the heart (heart attack).  Thus, coQ10 is often prescribed or recommended to prevent the cramping.  Some statin drugs now come with coQ10, but I don't know which ones.

 

Please note that the same arguments apply to red yeast rice, a natural supplement used to lower cholesterol.  It has a natural statin that is a mirror image of one of the prescription statin drugs.  Like the statins, it too can deplete coQ10 so it is often sold with the addition of coQ10.

 

At the end of the day, I believe that schlerotic deposits in the heart arteries cannot be explained with high levels of cholesterol alone.  You see, cholesterol acts like a glue on sites that are damaged, such as on micro cracks in blood vessels.  Cholesterol levels go up when there is stress (I supposed to suppress a loss of blood in a fight.)  The arteries near the heart can exhibit the highest number of micro cracks because of the huge pressure differentials they are exposed to.  If one is prone to bruising, bleeding gums, and other symptoms of weakened arteries, then it is likely that the heart arteries are clogged.  Scurvy (a Vitamin C deficiency) is a prime example.  Patients with scurvy are prone to bruising, bleeding of the gums, and heart attacks.

 

So if one is cramping (and there are many causes), it would be worthwhile to ask the doctor to check for mineral levels and all other possible causes with a blood test. 

 

As a note, statin drugs are often prescribed with diuretics that reduce high blood pressure.  Diuretics can deplete minerals and cause cramping.  It's always good to understand the cause of the high blood pressure to take the right action.

 

 

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Martib, Community Member
5/24/09 1:58pm

Found this response very helpful - seemed to be a balanced approach rather than "statins are bad" etc.

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Louis Showalter, Community Member
12/ 8/10 8:57am

I would suggest to anyone out there experiencing these problems to get to the root of the whole thing and see what Vitamin C. can really to rid your arteries of the plaque that is formed there,   Try www.vitamincinstitute.org  or just type in the GO LINE the following  PRACTICING MEDICINE WITHOUT A LICENSE and read some of the testimonies written there.    

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yiota, Community Member
6/17/08 7:24am

yes

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'Tis Himself, Community Member
6/24/08 1:55pm

Not long after making dietary changes and taking statin drugs, I experienced horrible leg cramps in my calves and feet. I changed my statin drug but the cramps continued. I read somewhere that lack of calcium could cause leg cramping and realized that I had not replaced milk in my diet with a calcium source. I then used a calcium supplement and the cramping disappeared within a couple of weeks.

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TonyB, Community Member
8/12/09 1:53pm

You bet statins cause cramps. I’m begging to think it’s the dirty little secret that is being kept from all statin users. I'm off statins for now and no more cramps, vibrations or trigger finger. It's so nice to sit and watch TV without the terror that comes with the precursor of an attack. My cholesterol is up from 185 to 295 in the 6 weeks or so since I stopped all statins (Crestor being the last). I meet with my doctor in 3 weeks so perhaps he'll have a plan. I read that statins in low doses taken with CoQ10 there are no cramps. I'd be willing to give that a try. Whatever we decide I want blood work every 2 weeks like a Coumadin patient to monitor my CK levels. Normal CK (Creatine Kinase) blood levels range up to 198 U/L (units per liter). My level was 540.

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ZeldaGlutch, Community Member
8/18/09 8:01pm

My CK is 1120 and the leg cramps and residual pains are horrible. I'd rather have high cholesterol!!

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carol, Community Member
9/27/09 12:08pm

I didn't know that statins caused the cramping I was experiencing, but I did discover Cramp Bark from Herb Pharmacy. As long as I take it 3-5 times a day I have no cramping now for over a year. I had already been taking lots of Calcium, potassium, and magnisium. I am on COQ10 to protect my liver from statins, but will now up the dosage. Cramp Bark is a life saver. I stock pile it!

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D. Connolly, Community Member
4/14/10 6:04pm

I take COQ10 also but that did not stop the foot cramps.  However if I reduce the med to 1/2 10mg and take it at night, it seems to help somewhat.  I do not get the cramps every day.

 

I have only just started this regimen and it make not work to reduce my chesterol but I will advise after 60-90 days.

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D. Connolly, Community Member
4/14/10 6:04pm

I take COQ10 also but that did not stop the foot cramps.  However if I reduce the med to 1/2 10mg and take it at night, it seems to help somewhat.  I do not get the cramps every day.

 

I have only just started this regimen and it make not work to reduce my chesterol but I will advise after 60-90 days.

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D. Connolly, Community Member
4/14/10 6:04pm

I take COQ10 also but that did not stop the foot cramps.  However if I reduce the med to 1/2 10mg and take it at night, it seems to help somewhat.  I do not get the cramps every day.

 

I have only just started this regimen and it make not work to reduce my chesterol but I will advise after 60-90 days.

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kssunshine, Community Member
4/22/10 12:26am

I was taking ZOCAR for over 2 years when I starting having horrible symptoms in my legs.  It seemed as if I had to literally "think" about taking steps.  Cramps were unbearable.  I got off the ZOCAR and the leg problems stopped. (cramps, myopathy)...I started 3 weeks ago on CoQ10 at my Drs. request and here come the cramps again.  I am starting to think that since I know I am not deficient on Calcium or Mag or really any other vitamin or enzyme that it is the Statin in the CoQ10 family (Dr. told me that CoQ10 actually is related to many Statins).  I stopped taking it a few days ago and the cramps are now gone hopefully NOT to come back.  I HATE the calf cramps...  I also take Fish Oil but I know that it is not causing any problems except maybe oily stools.

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socialgoddess53, Community Member
10/12/11 1:53pm

Get off those statins!  Red Yeast Rice (2400 mg), Non-flushing Niacin (1000mg) and Fish Oil (3000mg) will do the same thing as statins, with no adverse effects.  And fire your doctor and go see an holistic doctor.  That's what I did. 

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jj2010, Community Member
8/ 1/10 10:40pm

it's interesting to learn that the leg and foot cramps i have may be related to simvastatin...since i drink 16 oz of milk a day, take calcium + vitamin d and magnesium, a comprehensive multi-vitamin, B50 (thinking about changing to B100), and drink about 80 oz of water a day...i'm definitely thinking it's the simvastatin.  i'll talk to my doctor about it...he put me on simvastatin because cholesterol was 245, even though ldl to hdl ratio put me in a low risk category...i'm thinking i need to stop the simvastatin for three or four months, check my cholesterol and see where i stand in the ldl/hdl ratio once again...

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Heartattack Johnny, Community Member
10/14/10 8:55pm

I had a heart attack and my chl was 135/35 - the good number was too low, and they still put me on lipitor (and 10 other drugs). My triglyceride level was also pushing the envelope of being bad (too many carbohydrates). After 2 weeks I was being woke up every night with severe leg pain while on the medication.

 

I started taking calcium supplements, but realized this is not a good solution in my case. Calcium helps create blockage in the arteries when a person is under stress, especially at bends and branches in your arteries. I needed a stint in my artery, at a branch, which was caused by the stress of losing my job in a one income family.

 

What I did was lower my intake of fried foods and bad oils (some oils increase inflamation in your body, canola for one). Increased my fiber intake. I also focused on getting the good oils into me, including taking teaspoons of them if necessary - olive oil coats the inside and outside of your arteries; borage oil helps greatly also. A side benefit of taking these oils is that it helps thin the blood while it balances your oil and chl levels.

 

Unless you have a DNA reason for bad chl, you should be able to control your chl levels with diet changes (NO FRIED FOODS or FAST FOODS) and supplements if necessary. 2 years ago my LDL level was 212. I was able to get that down to 135 through diet modification and supplementation (I do not work out, though I should).

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crestor taker, Community Member
6/19/11 6:37am

I been taking Crestor for about 1 yr. I've been getting foot and leg cramps almost nightly for 9 months. I'm taking 4000 iu of Calcium - still get cramps- only at night. I take Crestor at night. When I get cramps, I drink 1 T of vinegar in about 1/2 c of water. Cramps then subside.

When I went on vacation and forgot the Crestor, I did not get cramps. Coincedence? Maybe.

I will take everyone here's advice and check on my CoQ10.

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Orlo Anderson, Community Member
6/24/08 2:34pm

Yes!!  I take Lescol and didn't attibute the cramps in my legs, feet and hands to that class of drug.  Initially, my MD prescribed Quinine and the cramping stopped.  Quinine can no longer be prescribed for that purpose.  As a substitute, I began using Calcium with Vitamin D and Magnesium which have eliminated the leg cramps and lessened the cramping of the feet and hands.   

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bebe, Community Member
6/24/08 4:37pm

You bet the statins are bad.  I went from Zocor to Pravachol  to Lipitor and now Zetia.  Am still waiting for the dam stuff to go away.  Docs do not understand when we tell them.  Stay away from Statins.  Help?

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bebe, Community Member
6/24/08 4:37pm

You bet the statins are bad.  I went from Zocor to Pravachol  to Lipitor and now Zetia.  Am still waiting for the dam stuff to go away.  Docs do not understand when we tell them.  Stay away from Statins.  Help?

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MIA TROISI, Community Member
6/24/08 4:58pm

MY DR RECOMMENED  COQ10 WITH MY STATIN - SINCE THEN I HAVE HAD NO LEG CRAMPS.  ASK YOUR DR.

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gcgranny, Community Member
6/24/08 7:09pm

I took Zetia for a little over a year.  The last 3-4 months I experienced terrible crampling everywhere....my sides, legs, abdomen, legs, arms, etc.  I researched all the meds I was taking on the internet.   The only one that cramping was one of the side effects was the Zetia.  Even called the company and described the symptoms.  They said I should maybe stop taking them.  After calling the dr. office to inform them of quitting, I did stop taking them.  The cramps disappeared approximately 2 days later.  About 7 mos. later the dr. decided to put me on something else...it is simvastatin.   Because I am afraid of all these meds whose side effects seem to be almost worse than the disease, I haven't begun to take the new drug yet.  Don't know what to do about it.

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Jann, Community Member
7/23/09 11:16am

i've been on 20 mg of Simvastatin for about a year.  It just dawned on me to google the above subject.  my cramps aren't bad in my legs and feet but i didn't have them before.     what side effects did you discover with Simvastatin?

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Tamlynn, Community Member
8/26/09 8:39am

I just started on Simvastatin last week and have woke up 2 times with cramps in my calfs.  I was on Lovestatin before and never had that problem. 

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gcgranny, Community Member
4/ 6/10 3:17am

I decided not to even try the simvastatin, so don't know about the side effects.  Had enough of the cramps and the constant soreness that resulted from the zetia.  Did have a cholesterol lab done in Feb. of this year, and my dr. didn't say anything about it being high. 

 

I take a lot of meds because of my heart...a diuretic, digoxin, coreg, lisinopril, magnesium, potassium, etc.  I have also declined to take meds for osteoporosis.  Too many side effects from so much of lots of meds on the market...and some of them seem more horrific than the original ailment.  I also take B-complex, vitamin C, and Co-Q 10...dr. didn't tell me to either, but some vitamins are water soluble, so because of the diuretics I take b and c...and the co-q 10 is supposed to be good for my heart.

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BOC, Community Member
12/11/09 10:21pm

I was on Lipitor for a couple years, with no cramps.  Then my insurance changed (Medicare) and they wouldn't pay for the Lipitor so I was changed to simvastatin.  I have had cramps in my feet, toes, calfs, abdomen, and fingers.  My doctor put me on CoQ10 which reduced the cramps, but have not stopped them.  They are very annoying.

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krystalbird, Community Member
4/ 5/10 7:12pm

I'm been on simvastatin for 1-2 months, experience intermittent cramping that's pretty bad. See my post today.

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Diane Cook, Community Member
7/22/10 4:06pm

I also am experiencing the cramps all over and have taken all the afore mentioned statins and just started Lipitir and am still having very,very bad cramps in my ankles ,feet and calves. I have just about decided to stop taking all of these meds and take a chance with my cholestrol. I don't want high cholestrol but want cramps even less. I also took the simvastatin and had cramps. Hope you find something that helps.

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Nancy, Community Member
4/13/12 8:33am

I was switched to simvastatin [40 mg] 2 months ago and 2 weeeks ago started with night leg cramps. Added a calcium wth vit. D and minerals. The night time cramps stopped but my leg started aching so badly during the day that I am taking acetaminophen every 4 hours around the clock to walk and sleep. I started taking a half of pill and I am still having problems. I am getting off these pills today after reading all of these comments from other people on this site. I am going back to Pravastatin 20 mg. I did not have any problems with that one. My new Dr. wants me to switch to Lipator. That is in her opinion the best of all the statins. Good luck. 

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Suresh Bhikha, Community Member
6/25/08 3:08am

Yes I agree with you. I suffer from cramps as a result of taking lipitor for my chlosestrol. I have been taking slow mag (magnesisum capsules) and have found that this eliminates the cramps at night. When I stop takingg slow mag the crramps return. I sugest you try slow mag to avoid cramps.

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Rula B., Community Member
6/25/08 9:58pm

I get leg and foot cramps but it is usually because I forgot to take my calcium (with vit. D and magnesium) and/or drink enough water.  For immediate relief I drink about 2 swallows of pickle juice.  That's what football teams use after and during a game.  Works for me!

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Okilloran, Community Member
10/ 6/10 5:03pm

What the heck is in pickle juice that would help with cramps?!  I have never heard of this before!  Smile

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grandma advice, Community Member
1/23/11 2:25pm

Pickle juice has vinegar in it.  A lot of natural remedy folks and older friends of mine take natural vinegar with the "mother" in it, supposed to do wonders for you.  So that does make sense to me!

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mike, Community Member
6/19/12 11:01am

It's the quick infusion of salt (brine) into your body, and it does help. I occasionally have cramps on the insides of my thighs that are excruciating. I have found that when the cramps occur, if I quickly drink two eight oz. bottles of water, a half cup or more of pickle juice (I keep a jar of dill pickle spears in my frige just for cramps) and then, walk, fast and hard, I can get rid of the cramp. Sometimes the cramp leaves my leg sore for two days, the same as if it was injured by trauma. I sometimes think dehydration is a also partial cause of these cramps, so I am very diligent about staying hydraded, and limiting my alcohol intake. Seems to work.

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mike, Community Member
6/19/12 11:01am

It's the quick infusion of salt (brine) into your body, and it does help. I occasionally have cramps on the insides of my thighs that are excruciating. I have found that when the cramps occur, if I quickly drink two eight oz. bottles of water, a half cup or more of pickle juice (I keep a jar of dill pickle spears in my frige just for cramps) and then, walk, fast and hard, I can get rid of the cramp. Sometimes the cramp leaves my leg sore for two days, the same as if it was injured by trauma. I sometimes think dehydration is a also partial cause of these cramps, so I am very diligent about staying hydraded, and limiting my alcohol intake. Seems to work.

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crestor taker, Community Member
6/19/11 6:29am

I take Crestor and only recently thought it may be the cause of my leg cramps. Never had them before. I take vinegar, 1 T in 1/2 C water, when I get the cramps. It takes about 1 min for cramps to subside. I'm going to ask the dr to check on my CoQ10.

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mike, Community Member
6/13/12 12:18am

is that a tablespoon on vin an half a glass of water?? an when do you drink it before bed?? or does it matter?? thank-you

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confucious, Community Member
6/27/08 1:55am

I was initially prescribed Zocor for cholesterol and I experienced leg and upper body muscle cramps.

However sometime later when the medication was changed to Lipitor, I didnot experience the cramps and still take lipitor, proved a lucky change for me.Try your luck with medication change it just might work. Good luck.Cool

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CESAR, Community Member
6/28/08 11:54pm

EVERY TIME I TAKE LIPTOR I GET CRAMP ON MY LEG AND ALSO A TRIGGER FINGER WERE IT CRAMP UP....WHEN I STOP LIPTOR IT GOES AWAY....

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TonyB, Community Member
8/ 6/09 7:16am

I have had leg cramps since I started taking statins. My doctor never connected these cramps and statins. I also developed a trigger finger. I was put on Crestor to drop my ttl #'s below 200. (Because I am a heart patient-had an aortic valve replaced)

 

Within 2 months on Crestor my ttl cholesterol level was 135 and the cramps were much worse. The final cramp lasted 15 minutes and the pain was unbearable. I was reduced to a screaming blob lying on the floor, unable to move...only scream in pain.

 

I went to the doctor and he took me off Crestor immediately. Some blood level went to 540 vs. no higher than 200...I forgot what). Also, I got a 9 inch by 6 inch black bruise where I had the thigh cramp. I was taking 250 mg of magnesium and 8 ounces of quinine water/day to help with cramping. I'm off all statins and no more cramps or leg vibrations (pre-cursor). I have increased strength in my hands and feel much better than I have in years. I now take 4 1000 mg fish oil and 100 mg CoQ10. I see my doctor in 3 weeks to come up a plan to control my cholesterol which has shot up to 295...even though I walk 4 miles/day, 6 days/week and I eat no more than 6 ounces of meat per week. I think I'm screwed.

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Diane, Community Member
7/26/08 8:27pm

I'm having foot and leg cramps in bed, and only in bed.  I can move in the night and the cramps start.  I take Lipitor.........not sure if this is related.

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krystalbird, Community Member
4/ 5/10 7:18pm

My experience is similar...cramps in bed.

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dbill, Community Member
7/10/10 12:38am

yes yes yes stop taking. I have severe foot and calf cramps on lovastatin in bed in the morning.

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krystalbird, Community Member
7/10/10 7:32am

Thank you dbill for your emphatic info. I stopped taking simvastatin - as well as lisinopril - after I awoke one night with a cramp so severe I almost howled like a wolf at the moon! I tried walking it out, stretching it out, nothing was effective. 

 

On lisinopril I also experienced dizziness & fatigue. At my age (77) who needs that? I want more energy, not less! Right now I'm on 2 meds, levoxyl & hydrochlorothiazide, & I'll stay with these as long as the 2nd one gives me no trouble.

 

The really annoying thing is that the dr. gave no warning that cramps like this could occur, & nothing to do about it if they did. And I consider him to be a bright, very competent dr.

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Ontario, Community Member
7/21/10 10:20am

Wow!  I am on Lipitor for several years, but just finding the last year the cramps in toes, feet and calves are nightly, rather than occasional!  If I skip a night dose, I do not get cramps.  The calf muscle pain will last into the next day, althought the cramp is over.  I will be making an appt. with my Dr. to talk about this.

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Okilloran, Community Member
10/ 6/10 5:42pm

Yes, my leg and foot cramps occur only at night in bed OR when I am lying on the sofa watching TV or reading.  Strange!  I recently started taking more magnesium, thyroid support, drink OJ and eat a banana at least once a day for potassium - still having cramps!  These didn't start until I was in desert and I think I may have gotten dehydrated though I drank a ton of water and also drank cellular renewal drinks for mineral replacement.  Since then, however, I've had these cramps which seem to get worse.  Also a strange, awful kind of "sensation" - maybe like restless legs?  I don't know! - in the evening. 

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knoxie, Community Member
5/ 9/14 10:39pm

I took Zetia for 1 yr and Crestor for 4. Several months ago I developed tightness and discomfort in my gluts,hamstrings and calves I have had muscle weakness, decreased calf muscle and horrible lower leg cramps. They only happen at night and are extremely painful. I try to walk them out but can't even stand. I wake around 4-5 am every day with this discomfort, odd, restless, sore calf sensation. I never related it to the Crestor as I had been on it for so long. I discontinued 3 weeks ago and still have the discomfort and occasional cramps. I had muscle pain all over but thought it was my inflammatory arthritis. I feel much better everywhere except my lower legs. After a sustained cramp my muscles are so sore for days every step hurts. Hoping tincture of time will help. Thank you all for all for your many suggestions. I plan to try to reduce my cholesterol with supplements and will try some suggestions for the cramps. I'm a nurse and have always felt that medication was the answer. Rethinking that....

 

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tandoir, Community Member
8/ 1/08 11:14pm

My husband also gets leg cramps with a variety of different statin drugs.  Just as a tip to those of you out there with bad leg cramps. ..keep a paper bag near you (esp at night)....breathing into a paper bag, making sure to make the bag expand and contract, relieves leg cramps within seconds.  The air changes the blood chemistry and makes the cramps go away.  I will ask my husband's doc about the remedies to prevent leg cramping like taking calcuim...thanks for the tip.

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wendy, Community Member
8/ 8/08 6:39pm

my Mum gets leg cramp taking statins do the doc,s know everything?

 

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AreJay, Community Member
9/12/08 3:19am

I have taken Lipitor and Lovastatin cholesterol meds and with in a week of taking them I started having severe neck and shoulder pain, my feet/heels hurt when I stood/walked for a short period of time. I work on a computer most of the day, and I noticed my wrist hurting so bad that I could not operate the mouse. Some times I would even have chest and arm pain on my left side. Felt like I had someone sitting on my chest. After I stopped taking them, all the different pains went away almost immediately.

I am now on Zetia and I still have foot cramps at night. Feet and wrist still hurt and my hands get cold as ice, but not nearly as much with the other meds. I still get the chest pains also, but very rare. I am going to start a calcium sup to see if that helps the nightly foot cramps and foot pain from walking. Maybe it will help stop some of the other aches and pains also. I sure hope so. I need my beauty sleep. LOL

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dawn, Community Member
11/ 6/09 4:53pm

They interfere with other hormone receptors particularly thyroid (they are known as dirty drugs) at cellular levels. Block certain receptors like the vit D and cortisol by having high affinity for those other receptors (as statins do) and cardiac problems and the calcium drop is to be expected.

Incidently in the days before certain blood tests high cholestrol was indicative (reliably) of low thyroid function due to low production of cells needing membrane which is the main use of cholestrol. Inflammatory problems cause the problems they prescribe statins for. Q10 might just save ur heart muscle from statins, take it :)

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Peter, Community Member
9/15/08 3:18pm

I was on Lipitor and had occasional episodes of heaviness in both my upper arms. I went off that, and then on and off Niacin, and was finally put on Lopid (Gemfibrozil). (I have Type II diabetes and metabolic syndrome, and was also on long lasting insulin, metformin, and lisinopril).

Last winter I suddenly developed excruciating leg cramps in both calves, worse at night but persisting all day long. After a month of taking Ca++ and Mg+ and vitamins with no success, I stopped the Lopid and there was a marked improvement. However the cramping lasted another 4 months, and towards the end of that time I developed knee pain, which turns out to be a meniscal tear. Going off the lisinopril and metformin eased the pain from fluid pressure on my knee somewhat, although there is still some residual pain. I think the cramping must have predisposed me to the knee injury, but I can't think of any precipitating events (I was not active much with the leg cramps).

 

Lessons:

1) take persistent muscle cramping very seriously, because there can be serious  consequences and doctors do not seem to take them seriously

2) there needs to be much more attention paid to the side effects of these medications -- and much more thinking about whether and when they should be prescribed. The patient information paragraphs given out with the meds are inadequate.

3) there needs to be a national (or even international) registry of patient-reports on side effects of drugs -- with millions of people taking these drugs, we would build up knowledge of their effects very fast. Why don't we (or can't we) have such a registry? This is a no-brainer, just like the cancer registries that we now have. Every time there is a symptom possibly caused by a drug, doctors should have a simple, fast way of reporting that possibility. We should not expect meds to have zero side effects, but we should have mechanisms in place to rapidly recognize them when they are occuring.

 

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Bill, Community Member
12/25/08 1:33am

I got the same response from my Doctor, I fear the Doctors believe what the Drug companies tell them, and they like the benefits they receive, so they don`t question weather the drugs might cause problems! I`ve had leg cramps and feet cramps like you, when I stoped taking the cholesterol drug, the cramps ceased. A coincides? I don`t think so!

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Uga Dano, Community Member
7/16/10 12:43am

My 49-yr-old recently healthy husband had to have his aortic valve replaced due to stenosis (stiffening) that prevented it from opening beyond a small slit.  They sent him home from the hospital with Lipitor and Metoprolol (for blood pressure).  I understood the need to keep the blood pressure regulated with the new valve and the healing, but I was scratching my head over the Lipitor.  I told him not to take any more of it till I could research it again because I couldn't remember what it was I had heard against it, but I remembered it being really bad for you.  A few minutes online with sites like knowthecause.com reminded me!  I then called his cardiac surgeon to ask if he'd had a cholesterol problem.  There was no record of his cholesterol levels.  I asked if the valve stenosis had been cholesterol/plaque related and the surgeon responded, "absolutely not."  I reminded him that the echocardiogram showed all vessels had been clean as a whistle, which he confirmed, then I asked why they had him on Lipitor?  He was silent for a moment, then said, "He doesn't need to take it.  You can have him stop taking it."  I have my hubby on an anti-fungal diet, taking ribose to replenish the stores in the cardiac muscle, and have him taking CoQ10 anyway based on Dr Sinatra's recommendations for maintenance, but he may be taking more than some of you who tried it to no avail.  I also bought the most easily absorbed form at a quality health food store.  I remember reading that statins actually DEPLETE your body of CoQ10. Your body makes its own CoQ10, everybody needs CoQ10 for every cell in your body all the time, and you actually need an "over-abundance" of it to be readily available in each cell in advance just to produce ATP which is the basic energy of life.  Just because whatever amount you took didn't stop your cramps doesn't mean CoQ10 didn't work.  The example that springs to mind is the FDA daily recommendation for 60milligrams of Vitamin C, which is barely enough to keep you alive.  I read the other day that you need at least 400mg/day to have ANY positive health benefit at all.  Now we are reading that if you are sick you should be taking a couple of 1000mg tablets every few hours!  So do the research, take the right dosage and frequency and the best bio-available form, and make sure you are taking other supplements that support lowering your cholesterol naturally and which build up the cardiac patient's body in all areas.  Read Sinatra's supplement/vitamin list for cardiac and other patients, and check out knowthecause.com every spare moment for a while!  My hubby, 6 mo post-surgery, now walks 7.5 miles every day, runs the middle 2 miles of that, and sometimes runs 5 miles of it. He says he feels great. Yah bless you and restore you!  --Ugadano.

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Jake, Community Member
1/11/09 9:14am

To Barb and all those who get leg cramps at night and who take cholesterol lowering drugs.  I have high cholesterol, and have taken lovasatin and simvastatin, and I get severe leg cramps primarily at night.  Extra dosages of calcium and potassium seem to help but I still get them.  The VA used to prescribe Quinine but that is now unavailable.  There is a product called "Leg Cramps" by Hyland, which contains Herbal Quinine and you can get it at the the local CVS or Snyders.  It comes in two different tablets, one is disolvable in the mouth the other can be taken with water.  They both seem to help but not completely.  I don't know the answer and my doctors don't either.  A good walking program will keep the legs conditioned and that seems to help too.  Good luck.

 

 

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Les, Community Member
1/11/09 9:26pm

I have been on Lipitor for over 10 years. About 1 1/2 years ago I started getting horrific cramps in my calves, feet and ankles at night. There were non-stop....awful pain....no sleep. Eventually I stopped taking Lipitor out of despertion and the cramps subsided for the most part. I finally told my dr that I had gone off the meds. After 6 months I was re-tested (results were ugly as expected) and doctor has now put me on Crestor. The very 1st night the cramps returned. The next night was even worse. I just started taking coQ10 to see if that helps. Apparently from reading this message board this is a fairly common problem. Why don't doctors listen?

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Sybil, Community Member
2/17/09 10:08am

Me too....After being on 20mg of Crestor for 2 years, I was recently switched to 40mg and these same cramps have been plagueing me at night also....what have you found out?

Sybil

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TonyB, Community Member
6/16/09 6:06am

I have had occasional very severe leg cramps for years...as long as I had been on Statins. I was switched from Lipitor to Crestor (40mg) to drop my cholesteol lower than 200(because I was a heart patient). With Crestor, I went to 135 on my cholesterol.  One day I got a leg cramps (both inner thighs) so bad that the total pain in 15 minutes was equal to all the pain I have had in my 69 years. I got a 9 inch by 6 inch black purple bruise. My doctor did blood work and took me off the Crestor immediatly and cramps are gone...as is the "vibration" in my leg that terrified me that another cramp was coming. As an aside I also developed a trigger finger...now gone. Although I complained of the leg cramps for years (very severe but no bruising) my doctor never did a blood test to see if the statins were at fault. I'll take my chances with the high cholesterol rather than the leg cramps. I started taking CoQ10 and will have my cholesterol tested in a month or so.

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Jane, Community Member
8/12/09 9:26am

The inner thigh pain you describe is identical to what I experienced. It was so severe that I fell to the floor in tears until it subsided. The "vibration" you describe is a precursor to the attack. I learned to stand up immediately and put pressure on my feet to avert it. Initially thought it was related to other conditions and/or drugs, but not to statins which I had taken in low dosage for years. I also had finger triggering,requiring surgery on one occasion.

 

My doctor thought that the biphosphonate medication was responsible. I had a special calcium test among others after an acute spasm which was normal.

 

Stopping the statin reversed most symptoms after a week or so. Symptoms recurred with starting it again.  I reduced the statin by taking half dose one day and full dose the other which decreased the cramps. Cholesterol levels were still decent although not ideal. Attributing cause and effect with medications is not easy. Better studies are needed.

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TonyB, Community Member
8/12/09 1:49pm

Jane, I'm off statins for now and no more cramps, vibrations or trigger finger. It's so nice to sit and watch TV without the terror that comes with the precursor of an attack. My cholesterol is up from 185 to 295 in the 6 weeks or so since I stopped all statins (Crestor being the last). I meet with my doctor in 3 weeks so perhaps he'll have a plan. I read that statins in low doses taken with CoQ10 there are no cramps. I'd be willing to give that a try. Whatever we decide I want blood work every 2 weeks like a Coumadin patient to monitor my CK levels. Normal CK (Creatine Kinase) blood levels range up to 198 U/L (units per liter). My level was 540.

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Jane, Community Member
8/12/09 9:26am

The inner thigh pain you describe is identical to what I experienced. It was so severe that I fell to the floor in tears until it subsided. The "vibration" you describe is a precursor to the attack. I learned to stand up immediately and put pressure on my feet to avert it. Initially thought it was related to other conditions and/or drugs, but not to statins which I had taken in low dosage for years. I also had finger triggering,requiring surgery on one occasion.

 

My doctor thought that the biphosphonate medication was responsible. I had a special calcium test among others after an acute spasm which was normal.

 

Stopping the statin reversed most symptoms after a week or so. Symptoms recurred with starting it again.  I reduced the statin by taking half dose one day and full dose the other which decreased the cramps. Cholesterol levels were still decent although not ideal. Attributing cause and effect with medications is not easy. Better studies are needed.

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Barb 2, Community Member
3/14/09 6:53pm

I'm sure statins cause night cramps. I take Lipitor Atorvastatin 10mg and get leg cramps several times a night.  However I find taking  Quinine  Sulphate 200mg does help  - I know it does because I've run out of Quinine and have had cramps 3 nights in a row.

My name is Barb too ! and live in England.

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pamela love, Community Member
4/17/09 12:17am

HI" MY NAME IS PAM AND I ALSO SUFFER FROM LEG AND FEET CRAMPS AND I ALSO TAKE CHOLESTEROL MEDICATIONS FOR MINE BUT ONLY ONE THING THAT BOTHERS ME

THE MEDICATIONS DO NOT HEAL THE PAIN OF LEG AND FEET CRAMPS I TAKE TWO KINDS OF CHOLESTEROL MEDICATIONS AND THEY STILL DON"T HEAL THE PAIN THAT

WE SUFFER FROM THE CRAMPS AT NIGHT OR ANY OTHER DAY THAT DOES NOT GO

AWAY? I ALSO SUFFER FROM A WHOLE LINE OF PERSONAL PROBLEMS THAT JUST CAN"T BE HEALED THESE ARE THE KIND PROBLEMS THAT MOST AMERICANS HAVE TO

LIVE FOR THE REST OF OUR LIVES? BUT WE GO TO THE DOCTOR BUT THE ONLY THING

THEY GIVE US IS MORE MEDICATIONS TO TAKE?

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pamela love, Community Member
4/17/09 12:33am

HI" AGAIN I DON"T KNOW IF YOU GOT THE FIRST PART BUT HERE"S ANOTHER ONE FOR

YOU. HI AGAIN MY NAME IS PAM AND I SUFFER THE SAME SYMPTOMS THAT YOU DO

LIKE I AWNSERED IN THE FIRST PART I TAKE TWO KINDS OF MEDICATIONS? I ONLY CAN GIVE YOU MY BEST AT THIS GAME AS MOST PEOPLE WOULD CALL IT BUT BETWEEN YOU AND ME IT"S NO DATEING GAME? BUT I KNOW JUST HOW YOU FEEL WE

CAN ONLY HOPE FOR THE BEST FOR ALL THAT HAVE THIS COMPLECATION I AND YOU

KNOW THAT THIS NEARLY THE END BUT NOT YET?  SO MY BEST ADVICE TO YOU IS TO

JUST DO LIKE ME JUST HANG IN THERE? WELL BETTER GO FOR NOW SEE YA" 

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Paul Tilling, Community Member
5/ 9/09 5:33pm

This might sound too simple but when you get night cramps, get out of bed and STAND on the leg/foot that is cramped.  The act of standing on it gives immediately relief and stops the cramp. It is amazing how few people seem to know this.

Of course you then have to get yourself back to sleep....

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krystalbird, Community Member
4/ 5/10 7:21pm

For some kinds of cramp this works, but for some I end up howling with pain as I feel the muscles &/or tendons spasming. Still, fighting it by getting up, just as you would with a Charlie-horse, seems the only way to go, because staying horizontal in bed doesn't seem to work well, either. Though honestly, having been trained years ago to get out of bed & walk or stand through cramps from let's say overdoing sports, it would be highly unlikely that I'd stay in bed.

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Jane, Community Member
6/11/09 1:43pm

My husband has taken several different statins over the years and has also developed severe night leg and foot cramps in the past.  I am a registered nurse, and from previous knowledge had him drink a combination of 4oz of tonic water with 4oz of sports drink before bedtime.  All cramps dissappeared.  He does this several times a week, not daily and it is very economical.  Tonic water contains quinine in small amounts which along with the minerals in the sports drink helps to prevent the cramps.  Hopefully this will also work for others.

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tolner123, Community Member
6/22/09 10:28pm

Absolutely I take zocor and get terrible leg cramps at night. Stop the Zocor and leg cramps dissappear. Start back on it and leg cramps in my calf come back.  definitely not a coincidence. Dr says leg cramps are not serious. But I am the one in pain.

 

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d321g, Community Member
7/16/09 6:59am

I took one brand of statin for about 2 weeks and began experiencing horrible leg cramps - something I had never experienced in my 50 years. My doctor took me off this drug and put me on a non-statin. The cramps ceased immediately. After 6 months he wanted me to go on another statin, this time with a lowered dose of 5 mg per day. I am 15 days into this drug and once again, the cramps began last night while I was sitting in a movie theater. I had to walk around for 20 minutes until they subsided. I will be talking to my doctor again today...

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Victoria, Community Member
7/24/09 6:49pm

 

this is unbelievable. we are all saying the same things in different words. to me, the root cause of my calf pain, leg pains are these statins. nobody listens to me, first i started with the physical therepist, he said, oh no! not after taking them for 10 years, i didn't agree with that statement, then i went onto a cardiologist, i got a stress test, circulation of the legs test, no problem, went onto my internist; between the last two drs., they have stopped me from the statins one says for 2 weeks, the other says one month, and then want me on zetia, non-statin, i don't trust these meds. they are making me disabled; i don't want to do anything, i am always in pain, you mean to tell me these drs. after hearing all of us complains about the pains, and they are real!, these drs., just go on their merry way. unbelievable, i am going to take my change and not take anymore statins, i am on a high blood pressure pill and tricor, and some vitamins and that is it for me, although i am so concerned what my lipid panel is going to show in a month. drs. and pharm. need to get together somehow.

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TonyB, Community Member
8/12/09 1:51pm

You bet that statins cause leg cramps. Have you doctor do a CK blood test.  I'm off statins for now and no more cramps, vibrations or trigger finger. It's so nice to sit and watch TV without the terror that comes with the precursor of an attack. My cholesterol is up from 185 to 295 in the 6 weeks or so since I stopped all statins (Crestor being the last). I meet with my doctor in 3 weeks so perhaps he'll have a plan. I read that statins in low doses taken with CoQ10 there are no cramps. I'd be willing to give that a try. Whatever we decide I want blood work every 2 weeks like a Coumadin patient to monitor my CK levels. Normal CK (Creatine Kinase) blood levels range up to 198 U/L (units per liter). My level was 540.

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Stewart, Community Member
8/22/09 11:30am

I was aware that a statin could cause muscle aches.  Last December I had knee surgery, and since then I have been walking with a limp.  For the last few months I have been getting cramps, only at night, waking me up, and in the lower part of my legs and feet.  I am used to having cramps in my calf, mainly after working or working out (probably not stretching enough.)  But these are the STRANGEST cramps I have ever had.  They are in places in my lower leg I have never had cramps in my whole life, and I am 58.  At first I thought they may be related to my current bad walking style, but I started looking up the statin issue.  I have been taking Simvastatin for a couple of years, and Lipitor before that, and have not had muscle cramp problems like this, until the last few months.

 

I will talk to my doctor about this.  Obviously, I am exploring the statin issue again.  These are the strangest cramps - by my ankles, the side of my leg, top of my foot.

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mrswag, Community Member
5/26/11 1:22pm

These are the same cramps I have. Down the side of the leg, and in the ankle. I used to get Charlie Horses but these are definitly different and hurt much worse. This morning I was moaning and eventually crying and my husband came in to see what the heck was wrong. Until you've had one, they're hard to explain. I started on a statin 2 months ago! 

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Ehmunah(faith), Community Member
9/11/09 6:04pm

I can almost agree, I would get a burning like pain from my hip down my leg where I couldn't walk or stand in one spot for too long. when I would go shopping I needed to find somewhere to sit quickly, I was miserable. I stopped taking my cholesterol meds for about 2 mon. and there has been a significant change ! now I'm on a different cholesterol med. and I don't suffer as much, there has to be something about that.Undecided

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Fresh Mix, Community Member
11/22/10 6:11am

Your description matches my experience some years ago.  I lived with a burning, heated sting accross my left upper leg for years and had no idea it may have been related to Zocor, which was the only drug I was taking.  If I stood at the sink, at the ironing board or at a rack of clothing while shopping, I had to sit down and take the pressure off of my leg.  I even had extensive neurological testing to identify my problem and nothing was discovered. 

 

Finally, years later, when I was walking (and not standing still) a few miles daily, the burning would again build up and I'd have to stop at the side of the road and stoop down, bending my knees, to relieve the pressure so that I could continue the walk. 

 

At about that time, my doctor switched me to Lipitor in hopes that my still high cholesterol would respond better to the new drug.  With Lipitor, the leg pain somewhat subsided, but remained and began to build up again.  That's when I finally made the connection that my problem was the statin drug.  She now has me on Crestor and I don't have the burning leg problem at all.  Hurray! 

 

However, after a few years on Crestor, I now have increasingly annoying and severe foot and leg cramps and cannot get through a night without waking 3 or 4 times to attend to the cramping.  This has just begun within the past month and is getting increasingly worse.  My husband is suggesting that I go off the Crestor for a few months to see if this is the cause.  I've also started taking QoQ10 about two months ago, at a friend's suggestion to take along with the Crestor (nothing to do with the leg cramps at the time).  Now I'm also wondering if the CoQ10 might be the cause of the cramping??

Confused!Embarassed

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CR, Community Member
9/17/09 4:37pm

I have had leg cramps, mostly at night, after beginning to take statins for cholesterol.  I also take a calcium supplement.  So, it appears the calcium does not reduce the leg cramping.

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grama653, Community Member
9/27/09 6:32pm

i have  had terrible  muscle cramps  in my feet at night.  it makes my muscles sore and hurts to walk the next day.   my legs are very weak also. i take 20 milgm. at bedtime.

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Sugor, Community Member
10/ 2/09 12:26am

Yes!!!!!  I don't know why doctors won't help people who have damage from these drugs.  I took lipitor and Crestor and had to stop each because of severe leg cramps.  I have diabetes and after a heart attack, I was told I had to take statin drugs.  They gave me Simvastatin and it seemed to be better (no severe cramps).  I have been on Simvastatin for 2 1/2 years and my only symptom was a strange feeling in my legs and weakness in my arms.  But, about a year ago I started to get this severe weakness in my legs and the distance I could walk constantly reduced until I could only walk for about 3-4 minutes before I couldn't breath and had to stop walking.  When I told the doctor about this and how it upset me, he said it was probably my back and I should have it checked.  I mentioned this to a friend who told me that the exact thing happened to her.  She immediately went off the drugs and within 3 days went on a walking tour of Washington DC with no problems since she has been off the drugs.  I went off of Simvastatin and I am still having trouble with my legs 2 weeks later but I can already walk for at least 20 minutes with no shortness of breath.  I recommend that you listen to yourself and if you feel it is the drugs giving you symptoms, get off of them as soon as you can.  There are several medical sites that have blogs that address the problems with statins.  They are very enlightening.  Check them out.

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Brenda from Knoxville, TN, Community Member
10/ 6/09 1:29pm

YES!

I have been taking Simvastatin (generic for Zocor) for about a month now and after about 2 weeks I felt small hints of cramping in my legs and feet. About 6:45 this morning I started getting extreme pain from cramps in my right foot. I jumped up and tried to walk and or bounce a little to get it to stop but it took about 20 minutes for the cramping to go away.

Years ago I was on my feet all the time on concrete floors and my legs would cramp. I would pretend to drop my pen or keys or look for something that needed to be picked up for an excuse to squat down to stretch my legs. I was told about vitemin E capsules. I doubted that it would work but I was desperate and so I did try it. After about 2 weeks I noticed a difference. After a month I noticed that I was not having to "pretend" to drop things any more. 

About 4 years ago I was injured on a job and could not work anymore. I was on certain medications and was told not to take the vitemin E while taking that medication. Now that I am not taking that I am starting to take the vitemin E capsule again. That, along with the prayers should work. Vit. E allows for better blood flow to your muscles and that helps. I was told all those years ago to take the "natural" vitamen. It won't hurt to try plus the vit. is good for you in other ways. One study is talking about how vit. E is being used for cramps during monthly periods.

Good luck and God Bless You!

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tinkertoodle, Community Member
10/25/09 1:00am

You bet they do. I was on lipitor 40 mg and was having progressively worse cramping in my legs to the point one session caused my hamstring to tear. my doctor recommended co q 10 it helped for a while then stopped working. I took magnesium and calcium supplements which also no longer work. The final straw came when i had a cramp that retore the already damaged hamstring and i could barely hobble for 4 weeks with every step being torture. I stopped taking the lipitor and what was a daily cramp session lasting 4 or 5 hours affecting my feet legs back and arms stopped abruptly and has not returned.

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syke, Community Member
10/26/09 5:56pm

Yes i have really bad leg and feet cramps due to cholestral tablets, mostly at night, but the pain of the cramps can carry on throughout the day. terrible and worrying

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Pere R., Community Member
11/ 5/09 9:28pm

I have taken various statin meds iver the last several years, primarily Lipitor and Zorcor.  My cramping just started about 2 or 3 weeks ago.  The last episode of cramping Tuesday, Nov 3rd started in the left calf and then about an hour later in the right.  I agree that the pain is excrutiating.  However, when the pain passes usually that's it.  Not this time.  When I awoke in the AM and tried getting out of bed, I could barely stand up.  It's now Thursday (my doctor's day off) and I'm walking with a cane like an old old man (I'm 64).  I will be knocking down my MD's door at 9:30 tomorrow to find out if it is indeed the Zocor causing my problem.  I didn't take the Zocor today, so I'll see if there's any improvment in the morning.

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marcy, Community Member
12/11/09 7:54pm

Yes I too have a problem with severe cramps.  I had taken Lescol for 3 yrs after my heart-bypass surgery.  Then the muscle pains and cramps started.  I was put on Lipitor and they became worse.  Since I have to take cholesterol medication for good it seems, I was prescribed the 10 mg Crestor drug - and the cramps, severe at times, during day and night, have started again.  I was told to drink a small glass of Indian tonic water which includes quinine but really I just do not feel fast-relief results. I am really at a loss as I know that pain in the joints and muscles could be serious........but should I stop or is there another remedy to reduce cholesterol in my case? I do get cramps even during daytime, sometimes, especially in my toes........at night they affect my ankles mostly.

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marcy, Community Member
12/11/09 8:07pm

Yes I too have a problem with severe cramps.  I had taken Lescol for 3 yrs after my heart-bypass surgery.  Then the muscle pains and cramps started.  I was put on Lipitor and they became worse.  Since I have to take cholesterol medication for good it seems, I was prescribed the 10 mg Crestor drug - and the cramps, severe at times, during day and night, have started again.  I was told to drink a small glass of Indian tonic water which includes quinine but really I just do not feel fast-relief results. I am really at a loss as I know that pain in the joints and muscles could be serious........but should I stop or is there another remedy to reduce cholesterol in my case? I do get cramps even during daytime, sometimes, especially in my toes........at night they affect my ankles mostly.

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Peachgirl, Community Member
1/12/10 1:36pm

I was (yes, was) taking 10mg of Lipitor for a little over a year and during that time I would have mild, annoying foot cramps and my heels hurt so bad to stand on when I first got out of bed I would wince with pain to walk.  I'm extremely active, working out 5-6 days a week and thought the heel pain was from the jumping up and down and plyometric exercises, so didn't put 2 and 2 together until I took myself off the meds. All pain and cramps went away.  I went off the meds (did let my dr. know), because I started researching statins and the side effects and they scared the living daylights out of me.  I wanted to lower my cholesterol holistically.  I purchased the book "Cholesterol Down" by Dr. Janet Brill and have been following the dietary changes for 3 weeks now.  My dr. agreed to let me try this approach for 6 weeks at which time I will have blood test to see if it works.  I will repost here if my numbers are satisfactory.

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Apljack, Community Member
1/12/10 3:18pm

I take Lipitor and started having bizarre cramping muscles in my feet and ankles. I realized it must be from the statin when I would have a cramps in both ankles at the same time and location (odd little muscle). I took Lipitor in the PM as recommended, but switched to to AM. Then I added CoQ10 300mg, taken in the evening, and my cramps 98% disappeared!

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Cal, Community Member
1/30/10 8:49am

Yes! I have been taking statins for about 10 years now. I have been through the line up of statins and have had different side effects with them all, with one common one Cramps. My inter thigh muscle would feel as if it were going to tear in two. Next day so sore I could bearly walk. My fingers cramp so bad I could not straighten them. When my rib cage cramped so badly I couldn't move I finally  awoke from my dream of lowering my cholesterol with statins. I thought what if my heart muscles do the same?????? I quit for a few days, go to the Dr. he told me to try this one, that one etc. after 2 pills the cramps are back so badly I can't function.

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whodathunk, Community Member
1/30/10 9:08am

YES!  I never put the two together but not it makes perfect sense.  I started taking cholesterol meds about 60 days ago and that's about the time the cramps started!    Cramps in the toes, feet and calves. Mostly at night but now during the day too. They're getting more frequent at night also.

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tommy, Community Member
2/ 3/10 9:53pm

YES, what works for me is 100mg CoQ10 w/ 1000IU vit. D3

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PIZAAME, Community Member
2/ 7/10 10:17pm

YES, I HAD THAT SAME PROBLEM WHEN TAKING STATINS BUT UNLIKE YOUR DOCTOR MY DOCTOR AGREED THAT THEY DO GIVE YOU LEG AND FOOT CRAMPS, SERIOUS ONE.  THEY CHANGED MY STATINS SEVERAL TIMES FOR AT LEAST THREE YEARS.  NOW IM ON SMALL DOSAGES OF TWO STATINS THAT SEEM TO BE WORKING.  AT FIRST I WOULD TAKE BOTH ONE NIGHT AT BED TIME THEN THE NEXT AND I WOULD GET A CRAMP.  I THEN STARTED TAKING THEM EVERY OTHER NIGHT THEN ONE ONE OF THEM UNTIL FINALLY I'M ON BOTH FOR THE LAST MONTH AND IT SEEMS TO BE WORKING FINE BUT FOR SOME REASON I CONTINUOUSLY SUFFER WITH GOUT....THEY PUT ME ON STEROIDS BUT WHEN THE TREATMENT IS OVER WITHIN 24 HOURS OR SO THE SYMPTONS WOULD RETURN.   I HAVE AN APPT TO SEE ANOTHER FOOT DOCTOR TO SEE IF IT COULD BE SOMETHING OTHER THAN GOUT.....

WELL I HOPE THIS HELPS.

 

HAVE A GOOD ONE.

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jean, Community Member
3/30/10 1:28pm

am on 2omg of simvastatin and have pains in both my legs bad when walking also get cramp in my feet and toes ended up in hospital twice last 2 years with pneamonia last time 1 month ago was told to up simvastatin to 40 mg after 2 days i had severe pain below knees gp told me to just take 20 mg but still getting pain in legs i am female age 62

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magicdeeds, Community Member
4/ 1/10 9:08am

I am on 20 mg slimvastin and occasionally had mild cramping in feet and legs, then suddenly had a very bad thigh cramp which left the area extremely sore to the touch for days after.  I am physically very active and am concerned with muscle/tendon tears with these meds.  I do take CO10 and calcium and vit D so probably helps, but don't know what to do because I don't want to give up the running, etc. but worry about clogging of arteries later in life.  I have started taking half dosage in am and half in pm, but am also thinking about taking full dosage every other day.  Doctors don't often listen, and many just don't get fully informed, they are in the habit of listening to the drug reps, rather than checking facts themselves.

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krystalbird, Community Member
4/ 5/10 7:06pm

Yes, not just cramps in feet, but legs & five minutes ago, horrible spasms of cramps in my left inner thigh. Horrible. I hate simvastatin's effects. Also it seems my heart rate feels up from time to time. I believe the statin tires me, too. Exercising while in pain can't be done, so weight loss is impossible.

I'm willing to give it the first couple months, but not more than that.

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D. Connolly, Community Member
4/14/10 6:01pm

Yes I have the same problem and my doctor seems to not think much of it either.

With my family history, it is important I take the chesterol meds, however, I really suffer with the spasms in my feet.  I have cut the med in half and take it just before bed time and it has reduced the spasm.  I do not get them every day.  I am not sure, however, if by cutting the medication that I am achieving lower chesterol scores.  I will advise shortly.

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D. Connolly, Community Member
4/14/10 6:01pm

Yes I have the same problem and my doctor seems to not think much of it either.

With my family history, it is important I take the chesterol meds, however, I really suffer with the spasms in my feet.  I have cut the med in half and take it just before bed time and it has reduced the spasm.  I do not get them every day.  I am not sure, however, if by cutting the medication that I am achieving lower chesterol scores.  I will advise shortly.

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NC_Growth, Community Member
5/30/10 10:51am

I am 69 and over many years have tried almost every statin with the same feet leg cramps at night. And like others, I'm talking real pain, not just ache. Drinking a full glass of water does make it stop after a few minutes, but I too just quit the latest Statin, and will talk to my doc on Tues.  Since I am petite (5'3, 120lbs) and walk daily and ride a bike outdoors daily, I wonder at the need to reduce my cholesterol levels at all. Could mine be genetic?  Does anyone have any natural remidies to lower those levels? 

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June, Community Member
5/31/10 8:45pm

I certainly do and they are driving me crazy.  I've gone off the statins (I've tried them all) and now I'm taking Red Yeast Rice pills (which are natural statins) with my doctor's approval but I actually think the cramps in my feet and legs are worse.  It's always when I try to sleep or I wake up with them.  Yes, I don't care what anyone says, it's the statins.  I went off all the meds for a few months and my legs and feet were fine.

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CHH, Community Member
6/ 4/10 3:56am

I've been taking half of a Simvastatin tablet each night for several months.  About a month ago, my knees began to ache terribly and my upper legs swelled.  At night the pain is excruciating but I wouldn't describe it as 'cramps' as others here have.  My pain radiates upward from the knees and downward from the hips and seems concentrated in the middle of the thighs although the entire upper legs ache - from knees to hips.  It is an intense ache with shooting pains.  There is no comfortable position in which to sleep.  My legs remain swollen and I am concerned.  I'm 69 years old and also take a diuretic for chronic high blood pressure and Avapro to help control the BP.  The aches/pains seem to be getting worse and I'm wondering whether I should stop taking the Simvastatin.  The comments that all of you have made have been helpful.  Has anyone else experienced pain that began in the knees?  Thank you for allowing me to comment.

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JBar595, Community Member
6/10/10 12:27pm

I feel most Doctors won't confirm what your going through because they don't want you to discontinue the statin drug. I was on them for seven years, not a night went by that I didn't have cramps in my legs and feet. I was always told, it's your age, your getting older. I scraped the statins along with my doctors.

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JBar595, Community Member
6/10/10 12:32pm

Statins do cause cramps, I was on them for seven years, not a night went by that I wasn't doing a jig trying to get the cramps out of my feet. Mr Doctor told me it was my age. I researched it and stated taking COQ10, over the counter. As I further researched I discovered statins can ruin your heart and muscles, do the research, it's out there. I no longer take statins and dumped my old Doctor. I exercie more, I'm sixty and my new Doc says I'm more like a 45 year old. Statins are dangerous, do your own research.

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JBar595, Community Member
6/10/10 12:35pm

Statins do cause cramps, I was on them for seven years, not a night went by that I wasn't doing a jig trying to get the cramps out of my feet. Mr Doctor told me it was my age. I researched it and stated taking COQ10, over the counter. As I further researched I discovered statins can ruin your heart and muscles, do the research, it's out there. I no longer take statins and dumped my old Doctor. I exercie more, I'm sixty and my new Doc says I'm more like a 45 year old. Statins are dangerous, do your own research.

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WAA, Community Member
6/13/10 2:37pm

After a suspected TIA I (63 years old) was put on Lipitor - Cholesterol went to 135 CK to 300 plus.  Went to Lescol and Cholesterol went to 285 but CK was OK.  Now on Crestor and took blood test last week with results still unknown.  All three initiated nightly severe calf cramps, occasional thigh cramps and nightly ankle tendon cramps that totally lock up the joint along with daily daytime finger and hand cramps.  When I skip the Statin for a few days they stop completely. Started CoQ10 4 days ago and first three nights were cramp free but they returned last night.  I'm seeing a neurologist, cardiologist and primary care physician and they all ignore my cramp complaints.  Next is to add the quinine in some work as I drink large amounts of milk and water each day.

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john doe, Community Member
6/14/10 7:37am

I do not use statin drugs and suffer from leg cramps every noight. I have tried everything... electrolytes,,, calcium, magnesium. lots of water,, stretching, walking  byc riding, rub on drugs advertised in the web, traumeel, tylenol, sleep meds.....you name it. Doctors, chiropracters, phys. therapists. all try everything

nothing helps. I am conviced that this will never be solved and try to catch them at the start jump out of bed and walk around and return to bed and try to get some sleep, I average two to three  such experiences each night .  I try to grab a nap during the day but it  is not the same as agood nights sleep.. Save your money on advertised rubs and meds and resign yourself to grinning and bearing this and be glad its not something much worse like cancer or another deadly disease. I have hreard of no person dying from leg cramps although i sometimes think you could do more damage trying all the weird suggestions. one serious and reputable MD even suggested vinegar and water at bedtime.no help. Work your way around this as best you can and enjoy your day life as much as possible and try""" not to let it get you downand into depression . Good luck. 

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john doe, Community Member
6/14/10 7:37am

I do not use statin drugs and suffer from leg cramps every noight. I have tried everything... electrolytes,,, calcium, magnesium. lots of water,, stretching, walking  byc riding, rub on drugs advertised in the web, traumeel, tylenol, sleep meds.....you name it. Doctors, chiropracters, phys. therapists. all try everything

nothing helps. I am conviced that this will never be solved and try to catch them at the start jump out of bed and walk around and return to bed and try to get some sleep, I average two to three  such experiences each night .  I try to grab a nap during the day but it  is not the same as agood nights sleep.. Save your money on advertised rubs and meds and resign yourself to grinning and bearing this and be glad its not something much worse like cancer or another deadly disease. I have hreard of no person dying from leg cramps although i sometimes think you could do more damage trying all the weird suggestions. one serious and reputable MD even suggested vinegar and water at bedtime.no help. Work your way around this as best you can and enjoy your day life as much as possible and try""" not to let it get you downand into depression . Good luck. 

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CHH, Community Member
5/18/11 1:23am

I am so sorry that you are experiencing such pain and sleep depravation.  One thing that you may have tried but not mentioned is milk.   If you have not tried it, two glasses of milk about 15 minutes befofe you retire for the night may help (a lot!).  It certainly won't hurt you to try.  Please, if you have not already done so, try drinking milk right before bed.  Whatever you try, you are wished only relief and calm, deep, peaceful sleep.

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Barbd, Community Member
6/18/10 12:34pm

Yes statins cause leg cramps!  Try taking CoQ10 with your statins.  It has really helped me.

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Cherie Belle, Community Member
6/20/10 2:35am

Yes.  They insisted I take a statin due to family history.  Each one caused problems.  The last one, Crestor, was fine in the beginning.  I didn't feel great, but it worked and the cholesterol went down.  Then, suddenly, I began experiencing the most horrible cramps in the arch of my left foot, which would work it's way up my to my calf.  I would be up most of the night, stretching, standing, massaging, etc.  I told the Doctor, he said to cut dosage, which I did.

It only became worse.  The cramps went to the other foot and leg.  One night I awoke and realized I was virtually a cripple, both feet were in horrible cramping pain, my calves were tingling and stinging and then cramping.  It was at that moment, I said forget this.  I am not listening to them any longer.  I am 45 years old.  My numbers were not too terrible.  I believe by diet and exercise, I can get these number down.  I could not continue w/o sleep and with this pain.

 

Now, it has been two months.  I still have the cramps and weakness, three or four nights a months.  Last night was a horrible night, the worst.  It was after walking airport for a long while.  It seems something has happened and if I do anything that taxing, such as exercising, walking for long periods, which I love,

the pain returns.  I NEVER had this before the statin drugs.

 

I am hoping it will go away.  My legs have been sore all day after last night and I am afraid it will happen again tonight.

They say take the CO Enzyme, whatever...they checked my levels and they were fine.  One medicine leads to another.  I am off it.  I can only hope I regain the strength in my legs and the cramps end.

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JGW Florida, Community Member
6/21/10 6:24am

Like Casey Stengel said, "It's deja vu all over again!"  I was taking simvistatin (Zocor) and got little sleep because of cramping in my calves and feet.  If I did strenuous exercise, I would get cramps in my thighs that were so painful, I was reduced to sobbing until the spasms stopped.  Docs were no help whatsoever.  Because the thigh cramps were seemingly related to increased physical activity, I figured maybe I was dehydrating and losing electrolytes.  I started with a shotgun approach adding calcium (Ca), potassium (K), and magnesium (Mg) supplements and the cramping all but ceased entirely.  When I exercised, I took them before and after the exercise after making sure there was no chance of accidentally getting to a toxic level of any of the metal ions.  I eventually narrowed it down to Ca and continue taking a Ca citrate supplement daily.  Eventually, I did convince my pcp that it was the simvistatin that was the problem so she changed me to pravastatin recently.  It's worse.  With nominal exercise, I have to take Ca 2x a day.

I had not heard about taking Co Q10 and will definitely give that a try.  Regarding the elevated CK levels, has anyone had the CK fractionated into MM (muscle), MB (heart), and BB (brain) components?  As I recall the MB fraction is highly labile.

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Debbie, Community Member
7/11/10 1:25am

I was taking simvistatin (Zocor) until January of this year. I had cramps in legs, feet, hand, even my eyes were twitching. I thought maybe I could lower my cholesterol by watching my diet.  The cramping and twitching went away after I stopped simvistatin. I recently had my cholesterol checked. It had gone up. So, I went back on the simvistatin. The cramps started almost immediately. My toes curl up and I can't uncurl them. It hurts so, so bad. I take CoQ10 and have taken this for the last 2 years, along with fish oil, calcium, multi vitamins, Vit D3. Does anyone have any suggestions?

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Anonymous Health User, Community Member
6/21/10 1:17pm

Yes, it is likely that you can experience cramps from the statin drug.  Your doctor should have advised you to stop taking the drug and revert to a diet that helps you reduce cholesterol.  My doctor told me that statins can effect people with the symptoms you are having. I was adviced to stop the drug as well.  I will not go into a complete diet program, but you can search the internet for cholesterol reducing diets. You don't have to depend on the drug.  Long time use can affect your liver as well. Hope that helps

Suzanne Combs

Mooresville, NC   

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SuzanneS, Community Member
6/21/10 1:18pm

Yes, it is likely that you can experience cramps from the statin drug.  Your doctor should have advised you to stop taking the drug and revert to a diet that helps you reduce cholesterol.  My doctor told me that statins can effect people with the symptoms you are having. I was adviced to stop the drug as well.  I will not go into a complete diet program, but you can search the internet for cholesterol reducing diets. You don't have to depend on the drug.  Long time use can affect your liver as well. Hope that helps

Suzanne Combs

Mooresville, NC   

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tim, Community Member
6/24/10 3:42pm

I took 20-40mg of Mevacor for 15 years and never had a problem.  Two years ago my doctor switched me to 40mg of Simvastatin at my request, because it's on the low-cost drug lists at Walmart, drug stores, etc.  Six months into Simvastatin, I started having leg cramps.  They've never been so bad that I couldn't stand up and walk off the cramps.  Starting a year ago, I noticed increasing muscle loss.  Six months ago, I started having severe abdominal cramping, which the doctors diagnosed as muscle spasms.  Also, I started having unsteadiness (weakness) in my walk, and I power-walk every other day.  Two weeks ago, I started having severe back and neck cramping.  It seems like everytime I overuse a muscle, I have sever pain for 3 days and heat doesn't help.  I started a medium glycemic diet, and my total cholesterol dropped from 185 to 138 in 3 months.  I'm going to request a blood test for my CoQ10 level.  I don't think it's ever been done.  Hopefully, I can find some relief soon.

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tim, Community Member
6/24/10 3:43pm

I took 20-40mg of Mevacor for 15 years and never had a problem.  Two years ago my doctor switched me to 40mg of Simvastatin at my request, because it's on the low-cost drug lists at Walmart, drug stores, etc.  Six months into Simvastatin, I started having leg cramps.  They've never been so bad that I couldn't stand up and walk off the cramps.  Starting a year ago, I noticed increasing muscle loss.  Six months ago, I started having severe abdominal cramping, which the doctors diagnosed as muscle spasms.  Also, I started having unsteadiness (weakness) in my walk, and I power-walk every other day.  Two weeks ago, I started having severe back and neck cramping.  It seems like everytime I overuse a muscle, I have sever pain for 3 days and heat doesn't help.  I started a medium glycemic diet, and my total cholesterol dropped from 185 to 138 in 3 months.  I'm going to request a blood test for my CoQ10 level.  I don't think it's ever been done.  Hopefully, I can find some relief soon.

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dbill, Community Member
7/10/10 12:30am

Yes, I believe so. I have been taking lovastatin for years and lately I started to get severe leg, feet cramps and numbness in fingers. I mainly get them in the morning. I've read that these are some side effects. I will stop taking and see where it goes.

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t ruok, Community Member
7/15/10 11:10pm

My doctor prescribed Pravastatin to me 4-5 months ago.  I had never heard of any side effects with this drug and did not connect the HORRIBLE leg cramps I've been having in the last few months with this drug.  I would get 'charlie-horse' type cramps from my right hip down to my foot several times a day and I would have to move my leg or walk around to relieve the pain.  At night, the pain would culminate while I was sleeping to extreme pain that would wake me up and I would have to pace the upstairs (limping) of my house for a few minutes to get the cramp out.  

Surprisingly, I saw my family doctor (who prescribed the Pravastatin to me) and he gave me an anti-inflamatory and ordered my an MRI -- he had no clue, apparently, of the correlation of cramps with statins.  A chiropractor I saw two days ago said, emphatically, to stop taking the statin.  I am two days off the statin and the cramps have completely gone away.  

I'd rather eat better and exercise more to get my cholesterol down.  I am questioning whether these (or any drugs) should be prescribed to anyone under a reading of 250.  The drug companies are out of control and the doctors prescribe too freely, in my opinion.

 

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Debbie, Community Member
7/22/10 7:13pm

I had taken Lipitor for several years, I noticed cramps in my hands, legs. Didn't realize that it could be the Lipitor. My company started paying for simvastatin. So, I changed to that. I took it for more than a year. Granted, my numbers dropped, the doctor was happy, but at this point not only did I have severe cramps in my hands, legs, feet even my eyes were starting to twitch. To make a long story short. I started using Chia seeds last Oct. I decided in Jan I would see if the Chia seeds helped the Cholesterol. I went off the simvastatin. All the cramps went away. I went back to the doctor the first of June and had my blood tested. Came back 248 total. So, I thought I should try the simvastatin again. Was back on it for 2 days and the cramps started back. SEVERE cramps. I stopped taking it, and have not had any more cramps. I am now trying Heart Savior, two capsules twice a day. Hopefully this will help bring down the numbers. Am going to try it for 60 days then be retested. I'll let you know how it goes.

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kathleen sweazey, Community Member
8/ 1/10 4:41pm

I am having exactly the same symptom and when I discontinue the lipitor the cramping disappears.  

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Cindy Phoenix, Community Member
8/ 3/10 11:06pm

I absolutely believe anti-cholesterol drugs cause extreme pain in the feet.  My husband was on Lovastatin for approx. 8 months, experience increasing pain in his feet - so I had him stop taking this drug and use an herbal remedy consisting of "red yeast rice" and "milkthistle" for 7 months, with gradual reduction in the pain in his feet.  At his annual physical, his doctor had him begin Tricor, and within 3 days of this medicine the pain in his feet increased so badly he thought he was going to die!  Again, I have had him stop this medicine but his feet pain is so bad that he is seeing a foot doctor about it, so we'll see what can be done to undo what the drugs have caused....

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Cindy Phoenix, Community Member
8/ 3/10 11:20pm
I absolutely believe anti-cholesterol drugs cause extreme pain in the feet. My husband was on Lovastatin for approx. 8 months, experience increasing pain in his feet - so I had him stop taking this drug and use an herbal remedy consisting of "red yeast rice" and "milkthistle" for 7 months, with gradual reduction in the pain in his feet. At his annual physical, his doctor had him begin Tricor, and within 3 days of this medicine the pain in his feet increased so badly he thought he was going to die! Again, I have had him stop this medicine but his feet pain is so bad that he is seeing a foot doctor about it, so we'll see what can be done to undo what the drugs have caused.... Reply
Linda, Community Member
9/ 9/10 7:14pm

Yes, i just recently went on statins 6 months ago , I noticed that I had a cramp in my right leg when sitting and when i put my leg back at my computer my muscle would cramp up and lock , then i noticed i was losing some of my memory , I told my doctor he said it was from exercising so I dismissed it .Then my recent trip I told the doctor again he said  it was nothing and put me on a higher dosage , i went from 10 mg. to 20 and the symptoms  got worse i had finger pain in the right finger very sharp and could not hold anything plus I noticed I was losing my hair, big time , cramps in my legs and feet at night in bed and I also noticed that I cramped up in the swimming pool and was getting very depressed .

i just went  on line to read other blogs and other peoples comments and it's the same all over .

No your not crazy it is happening and call your Doctor .

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chimes 44 - texas, Community Member
10/ 6/10 12:02pm

I am so grateful for this blog.  I have been struggling with an extremely low vitamin d level and I have very high cholesterol.  I have not had leg cramps but have had symptoms sort of like restless leg syndrome at night and it seems to be related to my levels of viamin d going down.  I am now on simvastatin 20 mg daily and have been for about six months.  When I first got diagnosed with low vitamin d levels, i had severe ear pain and my esophagus was cramping so bad that I could eat only small amounts at a time because of the pain it caused.  I thought that I had an aneurysm or something very bad due to the pain I was experiencing.  After about 2-3 days of being on the vitamin d it started getting much better until it was completely gone.  It seems that as soon as I am taken off of the vitamin d (50,000 IU weekly) my level drops again.  I thought that it might be related to the simvastatin, but now I just do not know.  There are days that I feel like I am losing my mind.  If anyone has had like symptoms or has any knowledge about this, please send it my way.  I am female and 59 years old.  chimes 44 in Texas

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Arnoldr70, Community Member
10/11/10 3:51pm

I have been taking Lipitor 20 mgs for almost a year now. I have been suffering from leg cramps but what is worse is that my toes in both feet get cramped as well. Also, every once in awhile I get these cramps in my stomach which are extremely painful until they subside. I take coq10 but that does not help at all. I will try the calcium like some bloggers say and let you know if it gets any better. I am a 59 year old male in Florida and an active athlete as well as a marathon runner.

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Gail Childs, Community Member
10/22/10 3:55pm

They definitely cause feet and leg cramps.  I was taking chlesterol medicine and started having leg and geet cramps.  I didn't know what caused them so I kept taking the choesterol medcine.  Finally they got so bad I was screaming in pain so I called the doctor.  He had me stop taking the medicine and within a couple of days they stopped.  He had me start taking them after about two weeks and they immediately started again.  That is when he took me off the medicine for six months.  After about six months we tried a differently choesterol medicine and I was doing fine until about two weeks ago when I started having leg cramps again.  I immediately called the doctor this time and he told me stop taking the medicine for three weeks and try again.  Unfortunately, note like the last time when they immediately went away I am still having cramps at night.  It has only been a week so I am going to wait another week before calling the doctor if they don't stop.  I'm not taking the medicine so if they don't stop I don't know what he will do.

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Gail Childs, Community Member
10/22/10 3:55pm

They definitely cause feet and leg cramps.  I was taking chlesterol medicine and started having leg and geet cramps.  I didn't know what caused them so I kept taking the choesterol medcine.  Finally they got so bad I was screaming in pain so I called the doctor.  He had me stop taking the medicine and within a couple of days they stopped.  He had me start taking them after about two weeks and they immediately started again.  That is when he took me off the medicine for six months.  After about six months we tried a differently choesterol medicine and I was doing fine until about two weeks ago when I started having leg cramps again.  I immediately called the doctor this time and he told me stop taking the medicine for three weeks and try again.  Unfortunately, note like the last time when they immediately went away I am still having cramps at night.  It has only been a week so I am going to wait another week before calling the doctor if they don't stop.  I'm not taking the medicine so if they don't stop I don't know what he will do.

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debbies done, Community Member
11/28/10 7:08am

From coundn't agree with you more. I have been on lipitor and crestor, I have never in my life felt the kind of pain in my legs, or anywhere for that matter.I woke up screaming 3 to 4 times a night becausee of a cramp in my right leg. My poor husband had to go to work with alot less sleep because of me screaming every time I had a severe cramp. I'am so DONE WITH THESE. I will watch my diet exercise more or do whatever, but not in this lifetime will any Dr. put me on that kind of drug again.  I myself am so tired of drug companys not testing this medications long enough, they want to hurry and put them on the market and we suffer the complications. ENOUGH IS ENOUGH If any of you remember the vioxx drug well I was one of those unlucky people to be on that and suffered the serious effects of a heart attack. No More Testing these new meds on me. I will take my chances on my own. Good luck to all but I'am done. To me these  cramps are worse than child breath, and that is quite painful lol. Take care and do what is best for you. I love my Doctor he is great, its the drug companys I will not tolerate. Put the drugs out there and see what happens, well not to me. They need to tests drugs longer and then give them to us. Just my opinion of course, which I think I'am still entiltited to.

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jgeorgesr, Community Member
10/30/10 11:21am

I am taking Gemfibrozil 600 MB for about 4 month and have been getting cramps in my calves and feet at night and when just watching TV.  I get woke up about 3 to four time each night and have to walk around to get rid of the cramps.  Gemfibrozil is not a statin.

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MELISSA GRANT, Community Member
12/14/10 8:01am

I experience cramps in both feet and both hands, I am taking a drug for high cholestrol however the cramps were there before taking the medication, I believe that BAD CIRCULATION is causing these SYMPTOMS.

 

I have had 2 clots on my leg and arm, and as such I believe that the blood flow is improper so I guess the CRAMPS relates to that..

 

 

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Gadesmidt, Community Member
12/26/10 5:39pm

I did, and cut my prescription in half. bad leg cramps/  also got a round of Espophogial Verices and almost died. I'm Ok now though.

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Fred M, Community Member
12/28/10 10:56pm

I am prescribed Crestor and Zetia.  I have complained of horrible muscle cramping, mostly in the evening.  The cramping is so bad that it literally twists my fingers and toes out of their normal shape.  Last week I was directed to stop taking the medications.  Since then I have had no cramping whatsoever.  I am wondering which of the two is the real culprit.  

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Connie, Community Member
1/12/11 12:23pm

Hi Barb.

My sister was on cholesterol meds and she went to Dr after Dr trying to find out what was causing her SEVERE pain.  She was at the point of thinking  disability as she could barely function.

One day she was watching TV when a commercial gave the side effects of the CHOL med (she was taking) and lo & behold  that was it. The very symptoms she had was a side effect. She stopped taking it and less than 48 hrs later she was pain free. She was so mad that apparently none of the Drs  looked at the drugs she was taking.

Soooooo, yes they can cause severe pain. Don't let the Drs tell you otherwise.

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Kay, Community Member
1/17/11 10:55am

I'm currently on TriCor (3 months) and I get terrible cramps in my feet and legs. My toes go stiff and it takes me several minutes to rub them out.  I get these in the day and night, but not every day or night. I'm scared it might happen while I'm driving. As you know these are very painful. I'm on a couple of other medications and wasn't sure which one is causing this. But with your question, I'm calling my doctor today.

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jaym, Community Member
1/23/11 1:57am

OMG I am on Crestor and I feel likr someone is trying to break my legs.I have been on this before and told my doctor and she put me back on this stuff. I cant take this. Over 5 or 6 bad episodes of cramps a day.

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sharon, Community Member
1/23/11 1:17pm

I have been fighting leg cramps for years and I too have tried all kinds of medication for high Cholestrol.Sometimes the muscles in my legs just move as though there were something under the skin just moving about or crawling,this is independent of cramps . .The leg cramps with medication make a normal life impossible.

 

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Camparitonic, Community Member
2/21/11 11:54am

I am convinced that some patients react to statins by being plagued with leg cramps (not to mention all the other side effects).  Both my partner and I have had this experience, although the doctors continued to tell us that we are wrong.  Best proof for me is that if I am off the statins I don't have any leg cramps. My present primary physician who is not only a medical doctor, but also a homeopath had put me on a regimen of Gugul Lipid with Red Yeast Rice but I react even to the statin in RYR with leg cramps (although not as severely).  I now have developed a trigger thumb (I already suffer with carpal tunnel syndrome on both wrists) and I was surprised to read on this blog that other patients have developed these symptoms and attribute them to statins.  At my doc's recommendation, I dropped the RYR and am adding Niacin (target: 1000 mg/day).  I have to work myself up slowly with the Niacin -- starting with 100 mg and increase the dosage over time.  I was advised to use regular Niacin, as the non-flush or time release kind doesn't seem to work as well.  Also, I will have to have my liver values checked periodically when taking Niacin. My partner, who has had bypass surgery is also on this regimen taking the combination of Gugul Lipid and Red Yeast Rice along with the Niacin.  He did not seem to have any leg cramps and his cholesterol values slowly decreased, but not fast enough for his cardiologist, who added Zocor and swears leg cramps are not caused by statins.  However, now my partner oftentimes awakes with severe leg cramps at night.  One last thought: If you don't get anywhere with your present physician, you might consider finding another who will listen to your very valid complaints and work with you getting you on an alternative treatment.

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Padma, Community Member
3/11/11 6:24pm

Yes they can. I have a sister who took cholesterol drugs. She started to have cramps in her right leg and ankle. She kept thinking she hurts herself some how just couldn't pen point when or how. She suffered with this for days and decided to call her dr. As soon as he heard about her leg he told her to stop the meds and see him the next day. She ended up with damage to the nerves in her leg and angle which the dr. said she will improve somewhat but it will never be totally back to normal.  Please if your dr does nothing go to another dr who will listen to you.
Good luck      

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sam, Community Member
5/17/11 7:05pm

it is a given that statins DO cause muscle cramps

we used to be able to take quinine for it, however the FDA has taken quinine off of the market

a simple blood test looking for the "cpk" will tell the dr what he needs to do

a drug called "baclofen"  will reduce the cramps

if your doc does not believe in the drug........get a new dr

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sam, Community Member
5/17/11 7:05pm

it is a given that statins DO cause muscle cramps

we used to be able to take quinine for it, however the FDA has taken quinine off of the market

a simple blood test looking for the "cpk" will tell the dr what he needs to do

a drug called "baclofen"  will reduce the cramps

if your doc does not believe in the drug........get a new dr

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Steven Sharp, Community Member
5/18/11 3:23pm

I stop taking Lipitor a year ago because of painful leg cramps mostly at night. I would have cramps while sitting as well. Most of the leg cramps would occure at night.  The "night cramps" stopped almost imediately. I have gone a year without a single episode. I had a high cholesterol count again last week. I took my first Lipitor tablet yesterday morning. Last night I had a horrible leg cramp, in my calf, that lasted at least 10 seconds. I feel this is proof beyond a doubt. I won't take another.

 

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c.neidig, Community Member
5/21/11 4:59pm

Absolutely...I have tried 3 different statins, and all three gave

me muscle cramps and charlie horses, whether moving or just

sitting.  The shin cramps were the most pain. The last pills I

took were Lipitor.  I tried them and got the cramps in my theighs, shins, feet, toes, and calves....though not all at once.

I got cramps during the day, and/or at night when it woke me up.    I stopped taking Lipitor for about 2 months, then I tried them again....and it didnt take but a few days to get the muscle

cramps/spasms , so I quit again and am waiting for the doctor

to come up with something else. I have a 227 cholesterol count as of this week.  Some people never get the cramps, but it is the one thing listed on the pharmacy info you get with the prescription, that I have trouble with...I have no other ill effects that are listed, and there are a lot. So good

luck with finding something that you can live with.

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Andria, Community Member
5/26/11 11:18am

YES my cholesterol med does cause BAD leg cramps  especially if I miss a dose.. UGH hurts my doc recommended take QCo10 an enzyme with it..:)

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GreenButterfly, Community Member
5/28/11 2:59pm

So glad I found this site!   I have been on Lipitor for years (although not good about taking it regularly) - and realized recently that taking it correlates with having AWFUL cramps, mostly in my right calf, but one time it was very high in my left thigh.  

I get the cramps at night, and they are so bad I'm afraid I'll pass out or die.  [and I worry about cramps elsewhere - like in my heart.   That's a muscle too, right?  So I'd be dead if THAT muscle got a cramp! ]

 The cramps go on and on and on.  and if I even think about moving they begin again.   If I wake up before a leg cramp really gets going, I can stop it by slowly and steadily straightening my leg and bending my foot forward/upward (to stretch the back of my calf).   This hurts too, and there is a residual ache that lasts a day or two - but it's way better than the full development of the cramp. 

 

Coincidence that my cramp problems started when I stopped taking CoQ-10???

I had been taking it (along with Glucosamine and Chondroitin, for arthritic reasons) and had run out of it, didn't get more).    I'm going to start the CoQ-10nright away, to see if that resolves the problem.

 

Time will tell - but if the cramps continue -I agree with other folks here - I'd rather have slightly high cholesterol, than these  horrific cramps. 

 

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funkygibbon, Community Member
6/ 6/11 7:36am

I have been on statins for 2 years. I get cramps, mostly in my legs and feet, at night and during the day, recently i've had predominantly foot cramps, whilst sitting, driving even swimming. This has now resulted in severe tendenitis in my right foot with swelling and inflammation, so I am disabled to the point that I cannot walk or stand, can put no weight on the right foot. The swelling has gone down with treatment, but the pain remains.

Is it safe to just stop taking statins?

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TRI Life, Community Member
6/ 9/11 9:48pm

At 50 years old, I decided (after the doctor highly suggested) to start taking Crestor because my cholesterol was 275. After 3 months I began getting cramps in my calves. I had started exercising about the time I started the Crestor. After the cramping, I took myself off the meds and decided I was going to lower my cholesterol through diet and exercise. Four months after taking myself off the meds and strenous exercise and good diet, I had my cholesterol checked and it came back at 185. My doctor was amazed. However this didn't happen without some hard work. I still have slight discomfort in my calves but they stopped cramping like they did previously. I really feel for those that are experienceing this cramping, it is painful. I have tried COq10 for the discomfort but hasn't had an affect. Although their is a little discomfort it is nowhere close to the cramping I experienced previously. After the cramping I vowed not to go back on these meds. I understand that eveyone can't get out and exercise like I am doing, but I made the decision to try exercise and diet to control my cholestrol. My exercise involves much work but I keep telling myself this is far better than the alternative. Best of luck.

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Linda Rosamond, Community Member
6/12/11 7:10pm

Two years ago I was given Gemfibrozil 600mg x twice a day and then told to take Prevachol 80mg at night. My left leg and foot have been cramping since then. When it cramps, all joints lock up, my foot turns inward and I cannot move my whole leg. It can happen when I have been walking, or just sitting , or just standing up. I have to have my daughter massage my leg and push my foot slowly back and forth until it is over. I have spoken to doctors and can't get a answer. I am just not comfortable taking a ton of drugs anymore. Side affects seem to cause more problems then it's worth.

 

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Sharon, Community Member
6/21/11 3:51pm

I came on here to get info on leg cramps and foot cramps and I saw this ....well I just started taking last week Lovastatin for cholesterol because i was in the hosp for an asthma attack and they just happen to tell me my choles was high  well taking this for a week now  and damm I was up all last night with leg cramps   wow

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Gloria, Community Member
6/27/11 4:06am

I take simvistatin because i had heart attack last year along with of couse many other drugs. When I have busy day like yesterday shopping, in and out of car bunch of times and all over mall and grocery store I get so sore. Today I felt like I got beat up I could hardly walk or move with out wincing from just plain muscle pain all over. Does anyone think that CoQ10 would help with my problem..very sore feet as well. Any advise will be greatly appreciated. Thanks Glo

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sol liebster, Community Member
7/22/11 5:58am

I had been told this by someone who stopped taking statins and started to take Tomato Yeast Rice instead, who swears by this.  My leg cramps are described in the question above exactly.

I have also been suffering from Fatigue, affecting work, play, and now emotions. This same person (a doctor, NOT my internist or cardiologist) says the same statins may be the cause. I sometimes start to nod off while at desk or working in clinics, or just relaxing.  Situation becoming very distressing.

While on these statins for 2 years, my cholesterol "numbers" have improved to a normal range, so I am wary about ceasing statins. Is using the Yeast Rice a way to lessen the effects but maintain some cholesterol control?

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2fast4u, Community Member
7/28/11 11:31pm

Red Rice Yeast is a natural statin, in fact the original Lovastatin is a by product of RRY, and may produce the same side effects of any statin on the market. The real problem with this product is that it is marketed as a supplement and as such is not subjected to normal FDA regulation concerning production. The main issue is that there is no consitancey in the amount of statin you are receiving when you take this product which makes it very difficult to predict the outcome.

 

If I were on a statin and experiencing muscle pain, I would ask my doctor about trying another statin or adjusting my dosage. Not all statins are the same, different statins work through different processes so side effects can be less with one over another depending on your body's reaction.

 

Hope thins helps,

 

Jon

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corky, Community Member
7/28/11 10:38pm

I cannot take statins so that is not my problem.  wish it were that easyCry

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BeachBum50, Community Member
8/18/11 3:24pm

I have been taking Simvastin for a couple of years now, after insurance stopped coverage on Lipitor.  I get severe leg cramps 2-3 nights a week.  We're not talking about the kind of cramps that you can walk out.  It is the most intense pain I have ever experienced.  The only thing I've found that helps is a product called Biofreeze.  After I apply, the cramp will release in about five minutes.  Knowing that it WILL be gone shortly carries me through the pain.  I was glad to find this site and read all the feedback.  Gives me great argument to present to my doc during my next visit.  Foot in mouth

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H. A. GILLIS, Community Member
8/29/11 12:25am

I WAS JUST RESEARCHING STATIN DRUGS AND SIDE EFFECTS AND RAN INTO YOUR QUESTION.  YES, STATIN DRUGS ARE A CAUSE OF LEG CRAMPS.  MY HUSBAND HAS BEEN SUFFERING WITH THIS SINCE HE STARTED TAKING STATIN DRUGS.  HE QUESTIONED HIS DR. ABOUT THE LEG CRAMPS AND WAS TOLD THAT IT WAS PROBABLY CAUSED BY HIS CHOLESTEROL MEDICATION.  MY SUGGESTION IS ALWAYS GET A SECOND OPINION.  SOMETIMES DR'S HAND OUT MEDICATION LIKE CANDY. WE ALL KNOW HOW THEY'RE HOUNDED BY DISTRIBUTORS AND HOW THEY GET KICK BACKS ON PRESCRIPTIONS.  WE DON'T REALLY KNOW HOW MUCH RESEARCH THEY DO BEYOND THE INFORMATION PROVIDED BY THE MANUFACTURERS. SO, IT'S OUR JOB TO INVESTIGATE WHAT WE ARE PUTTING IN OUR BODIES. WE HAVE TO BE OUR OWN MEDICAL ADVISORS IN TERMS OF FOLLOW UPS. TRY A HEALTHIER DIET AND EXCERCISE TO CONTROL YOUR CHOLESTEROL.  GOOD LUCK

 

 

 

 

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H. A. GILLIS, Community Member
8/29/11 12:25am

I WAS JUST RESEARCHING STATIN DRUGS AND SIDE EFFECTS AND RAN INTO YOUR QUESTION.  YES, STATIN DRUGS ARE A CAUSE OF LEG CRAMPS.  MY HUSBAND HAS BEEN SUFFERING WITH THIS SINCE HE STARTED TAKING STATIN DRUGS.  HE QUESTIONED HIS DR. ABOUT THE LEG CRAMPS AND WAS TOLD THAT IT WAS PROBABLY CAUSED BY HIS CHOLESTEROL MEDICATION.  MY SUGGESTION IS ALWAYS GET A SECOND OPINION.  SOMETIMES DR'S HAND OUT MEDICATION LIKE CANDY. WE ALL KNOW HOW THEY'RE HOUNDED BY DISTRIBUTORS AND HOW THEY GET KICK BACKS ON PRESCRIPTIONS.  WE DON'T REALLY KNOW HOW MUCH RESEARCH THEY DO BEYOND THE INFORMATION PROVIDED BY THE MANUFACTURERS. SO, IT'S OUR JOB TO INVESTIGATE WHAT WE ARE PUTTING IN OUR BODIES. WE HAVE TO BE OUR OWN MEDICAL ADVISORS IN TERMS OF FOLLOW UPS. TRY A HEALTHIER DIET AND EXCERCISE TO CONTROL YOUR CHOLESTEROL.  GOOD LUCK

 

 

 

 

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Pat Wood, Community Member
9/ 6/11 3:43am

Yes I also get severe foot cramps at night from the statins. I was on 40mg and have now reduced the dosage to 10mg but the cramps still persist. I ahve been advised to take potassium to assist with the cramps.

 

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Pat Wood, Community Member
9/ 6/11 3:52am

I have been taking 2 herbal tablets every morning called Guggul by Himalaya products, my cholestrol control has come down from 15 to 5 in three months. Of course the Dr attributes it to the statin's but I know better. Try it it's fantastic, especially for people with hyperthryoidism. My thryoid count came down from 84 to 20 also in three months. You can also combine the guggul with Garcinia by the same people for lipid control.

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keely p, Community Member
10/ 4/11 7:07pm

Almost two years ago my Father who is 54 started having muscle pain, especially in his feet, about 4 months after starting Lovastatin. He went to the doctor but the connection was not made or even considered and he continued to take Lovastatin. His condition has worsened and is having so much muscle pain that he went to the ER a couple of weeks ago where they ran all kinds of tests, MRI, x-rays, etc and found nothing.

It has gotten worse even though he has stopped taking Lovastatin. He has lost about 30lbs and his cholesterol is now normal and he no longer needs blood pressure medication but walking is extremely painful and difficult. The pain has advanced to his hands and is going up his arms. He is experiencing other symptoms of myositis and rhabdomyolysis..

He's been to several specialists and no one seems to know what is wrong. Originally his doctor thought it was gout, but when the pain didn't lighten up they sent him to another specialist. The pain is now so bad that he has had to shut down his company and cannot work. He uses a wheel chair to get around...

I've read more articles in which people state their pain went away after stopping Lovastatin, so why is my father still in pain?? Will it ever go away? Will he ever be able to walk again? And why didn't his doctor take him off this horrible medication two years ago when the pain began?!

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socialgoddess53, Community Member
10/12/11 1:49pm

Yes they do!!!!! And they can cause permanent muscle damage!!! My doctor told me the same thing and I fired him!  I had cramps from my things to my toes!  When I had them at work, I quit cold turkey!  The pharmacist also told me to stop taking them.  I then went to a holistic doctor.  He placed me on Red Yeast Rice and Non-Flushing Niacin and Fish Oil.  I take 2400 mg of Red Yeast Rice, 1000mg of Non-flushing Niacin and 3000 mg of Fish oil.  My cholesterol went down over 100 points!  Imagine that!  All those vitimins are natural and the body will not reject this.  I have been on this regimine for 3 years now.  Of course, I watch what I eat but cheat at times.  I am 61 and look and feel great.  See a holistic doctor!  It might save your life and your suffering!

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Norm, Community Member
11/ 6/11 6:47am

I never had leg cramps in my life until I started taking lipitor a couple of years ago. The doctor doesn't seem to care about the side effects because she increased the dosage from 20 mg to 40mg . I took it upon myself to cut back as I please and I feel much better that way. My cholesterol isn't that high anyway at 3.5 mmol/l for LDL but the doctor wants it under 2 mmol/l .

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sacks 01, Community Member
11/10/11 9:14am

Yes I am taking statin and yes my leg cramps at night. I have been on lipitor and so far I have not had that problem I take 20mg of Lipitor

 

 

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sacks 01, Community Member
11/10/11 9:14am

Yes I am taking statin and yes my leg cramps at night. I have been on lipitor and so far I have not had that problem I take 20mg of Lipitor

 

 

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sacks 01, Community Member
11/10/11 9:14am

Yes I am taking statin and yes my leg cramps at night. I have been on lipitor and so far I have not had that problem I take 20mg of Lipitor

 

 

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Ironman, Community Member
12/16/11 8:55pm
Yes. I have been taking Lipitor for a few years with my cholesterol still stay high. Two weeks ago, my Dr. doubled my dosage to 40mgs. Last night I was awaken at 3am with extreme leg cramping. It envolved both legs and feet and toes. I also had diarria and vomiting until 7am. In the morning, I was sitting on the couch and the cramping continued. I am not taking my Lipitor anymore. It was all caused by Lipitor. Anyone else? Reply
Ironman, Community Member
12/16/11 8:58pm
Yes. I have been taking Lipitor for a few years with my cholesterol still stay high. Two weeks ago, my Dr. doubled my dosage to 40mgs. Last night I was awaken at 3am with extreme leg cramping. It envolved both legs and feet and toes. I also had diarria and vomiting until 7am. In the morning, I was sitting on the couch and the cramping continued. I am not taking my Lipitor anymore. It was all caused by Lipitor. Anyone else? Reply
Ironman, Community Member
12/16/11 9:03pm
Yes. I have been taking Lipitor for a few years with my cholesterol still stay high. Two weeks ago, my Dr. doubled my dosage to 40mgs. Last night I was awaken at 3am with extreme leg cramping. It envolved both legs and feet and toes. I also had diarria and vomiting until 7am. In the morning, I was sitting on the couch and the cramping continued. I am not taking my Lipitor anymore. It was all caused by Lipitor. Anyone else? Reply
H.D.W., Community Member
9/ 7/12 12:25pm

Yes, I have been on Lipitor and Ezitrol for years and I as well have numberous leg cramps during the night. Even if I just attmept to roll over generally my ham string muscles cramp.

 

At times when just sitting watching TV or what ever and attempt to get up, my upper thigh will cramp severally.

 

Calf and foot cramps occur as well at night but not as often.

 

 

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david x, Community Member
10/15/12 11:11pm

YES! My doctor said to watch for "muscle weakness." He claims he also said "muscle discomfort." Who cares? Both are vague descriptions, especially for an older person. Cramps aren't vague.

   Simvastin at a very small dose caused foot cramps, then hamstring cramps, calf cramps--and finally MASSIVE cramps in both calves while in bed--causing tearing and pain that's lasted for 3 months so far. From intense 2 hours hikes, I couldn't walk around the block--seriously!

   I also got bruising and huge muscle tightening. And when I got my flu shot, the nurse asked, from so much bleeding, if I was on blood thinner. Then the bruise for 3 weeks--from a flu shot. This was not my body!

   Statin need better warnings!!!!!!!!!!!!  If you're one of those hurt by statins, you deserve to know what might happen. And ALL these things can happen at very high levels of intensity.

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Barb, Community Member
3/23/13 12:37pm

Of course they can!  Why do doctors INSIST that a patient is not experiencing what they KNOW they are experiencing, especially when nothing else has changed in that person's intake and activities?  I was on statins for several months before the cramps started, and then after a year they were unbearable.  I stopped the statin meds and the cramps subsided within 2 weeks.  I started them again and the cramps returned.  Stopped and they went away. Then I started taking CoQ10 with red rice yeast and the cramps returned.  A nurse explained to me that the red rice yeast has a naturally occurring statin.  So stopped that and the cramps went away. It makes me so angry when docs won't listen to the patient.  OF COURSE their drug distributor is not going to tell them about the side effects. I thought it was common knowledge by now, in the medical community, that statins have that sort of side effect.  I would rather die younger and have a full, rich, enjoyable life than live as a cripple and live longer.  It had gotten to the point that I couldn't play with my grandchildren, couldn't get in positions needed for my work as a sign-language interpreter (for instance, interpreting a CPR training, on the floor), and it even interfered with being intimate with my husband.  I hope you will be able to find what works for you, and that you have found a doc who will LISTEN to you :) 

Sincerely,

A fellow sufferer

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North Carolina, Community Member
3/25/13 10:28am

I had cramping in my legs and buttocks so severely that walking became almost intolerable.  I was not sleeping due to the pains and cramps.  The doctor sent me to physical therapy for the cramps.  The therapist was surprised/concerned at the massive cramping from my waist to my ankles.  She had been working on me for several weeks with limited success.  Then I read that statins can cause muscle cramping.  I have stopped taking it!!  I am almost cramp free...but the cramps have caused bursitis in both legs.  My doctor is not interested..as he has put me on a different statin. (Which I refuse to take)

My cholesterol is high again.  I have been eating almonds and avocados thinking that the fat content would not affect my cholesterol numbers, but would benefit my health.  Who knows.

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djr100, Community Member
4/23/13 6:51pm

Barb

 

If you start taking 400 IU of Vitamin E while still taking the statins your leg cramps will go away. I now know 4 people who had the same symptoms while taking Lipitor - leg cramps almost every night. Once they all started Vitamin E the leg cramps went away within 2 days. 200 IU did not work.

dave r

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S, Community Member
7/18/13 11:13am

I have had bad leg cramps at night. After reading the many solutions that seem to work for some people and finding some solutions for me I arrived at this two pronged approach that seems to work well.

 

First, the one thing I noticed about people who cure their night time cramps by taking some supplement (calcium, magnesium, etc.) is that they drink water to down the supplement. The supplements change but there is always water. I tried drinking a glass of water when cramps would wake me up and it worked. I believe the extra water helps the transport of elements across the cellular walls. I think many night time cramps are related to not drinking enough water at night because we do not want to wake up to go pee. An interesting tradeoff. 

 

Second, I started taking 10 mg of creatine monohydrate daily. Creatine I think helps the formation of ATP, which may be affected by statins. Weight lifters take creatine to increase strength. It is said that it forces more water into the muscles. I don't know if this is correct but after taking the creatine I stopped having the leg cramps.

 

S

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Jeff, Community Member
9/18/13 9:11pm
I absolutely believe there is a connection between the statin drugs I have used and leg and foot cramps that I get (mostly at night in bed, but also if I am walking and somewhat stressed, like hiking/climbing). It was worst with Lipitor and somewhat better with simvastatin. A dream involving leg exertion - like jumping - can trigger wicked calf cramps. Exposing my legs to cool air or a breeze can trigger inner thigh cramps, which are the worst. I have come close to passing out on some occasions, and the muscle gets as hard as a rock. I recommend keeping your legs covered at night, even in warm weather. I find no correlated relief from taking calcium or quinine water. Reply
Col. Klink, Community Member
1/29/14 3:17pm

I've been on statins since 2001 and on Crestor for the last 4 years. About 2 years ago I started having severe calf and inner thigh muscle cramps in both legs. I had always had foot and hand cramps while on statins but never put two and two together. When the severe leg cramps started I told my PCP I thought they were being caused by the Crestor. She laughed it off and told me to drink more water and take potassium supplements. That didn't help, of course, and in the summer of 2013 I had a series of parallel leg cramps in both calfs and both inner thighs and both hamstrings. It was like a sceene from a horror movie. The pain from all the muscles cramping at the same time made me scream and vomit for the 10 minutes that the cramping lasted. After recovering from that evening I had a lingering pain in my right calf that would not go away. It was a deep pain that would hurt more after standing and then "stretch" itself out as I walked but would not go away. I told my PCP and she sent me for a sonogram of my right leg, thinking it may be a DVT. The sonogram came out negative and I was sent on my way with a diagnosed muscle pull. But the leg pain was not going away and about a week later I woke up feeling very short of breath. I couldn't complete my morning shower without needing to sit and catch my breath. This was not good.....I called my PCP and she told me to go to the ER. Well......the ER found my shortness of breath was due to a triple pulmonary embolism (blood clots in both lungs) and my leg pain was due to a DVT (blood clot) in my right calf. So.....I did have a DVT but they missed it when they did the sonogram and a week later it broke apart and caused PE in my lungs. I was in the hospital for three days and was told by several physicians (including my PCP) that I am very lucky to be alive. I was only 42 at the time of all this and otherwise in very good health except for my cholesterol. I have just recently completed my course of blood thinners and all my scans show no more clots or residual scaring so I am one of the "best case" scenerios of this situation. So......I attribute my DVT and eventual PE to my severe leg cramp which was caused by the Crestor. Needless to say my PCP is listening to me now and we are working to lower my cholesterol using other methods. For those of you with constant and severe calf cramps please beware of DVTs. 

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GRT, Community Member
2/ 9/14 12:42am

I, too, have what sound like the same problems.  I had heard statins were the culprits but have also heard duiritics like Maxide, which I take, also cause these cramps.  However, I have taken both of these drugs for years without cramping and now I have cramps nightly.  I have also heard that thyroid problems can also cause cramping.  I have had some tests which point to a thyroid problem but no doctor, endocrinologists, GPs, have been able to make a definitve diagnosis.  I am going to stop taking my statin drug for a few days and see if the cramps cease or lessen.

Very frustrating because these cramps force me to take an over the counter medication for leg cramps nightly.  I'm not sure if that is the right thing to do either.

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We hope you find this general health information helpful. Please note however, that this Q&A is meant to support not replace the professional medical advice you receive from your doctor. No information in the Answers above is intended to diagnose or treat any condition. The views expressed in the Answers above belong to the individuals who posted them and do not necessarily reflect the views of Remedy Health Media. Remedy Health Media does not review or edit content posted by our community members, but reserves the right to remove any material it deems inappropriate.

By Barb, Community Member— Last Modified: 05/09/14, First Published: 06/13/08