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Hi Ron, There is a link between low cholesterol and increased depression/anxiety. Cholesterol is a key component of nerve membranes/receptors and low levels of cholesterol may cause fewer than normal brain receptors for "feel good" neurotransmitter serotonin. It's possible that supplementing your diet with omega 3 fatty acids may alleviate symptoms of depression/anxiety; however, as long as you are not experiencing symptoms I see no reason to be concerned about a low total cholesterol. All the best, Lisa Nelson, RD, LN The Heart of Health - Heart Health and Weight Loss Tips

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