Generic Name: NIACIN EXTENDED-RELEASE/SIMVASTATIN - ORAL Pronounced: (NYE-a-sin/SIM-va-STAT-in) Niacin-simvastatin Oral Precautions
Before taking this product, tell your doctor or pharmacist
if you are allergic to niacin or simvastatin; or if you have any other
allergies. This product may contain inactive ingredients, which can cause
allergic reactions or other problems. Talk to your pharmacist for more
Before using this medication, tell your doctor or
pharmacist your medical history, especially of:
Before having surgery, tell your doctor or dentist about
all the products you use (including prescription drugs, nonprescription drugs,
and herbal products).
This drug may make you dizzy. Do not drive, use machinery,
or do any activity that requires alertness until you are sure you can perform
My mother-in-law has been visiting with us for the past few weeks. She remarked one day while peeling a mango how she felt as if she had a kindred spirit with citrus fruit, but was quick to also mention how disappointed she was to learn that she is no longer able to eat grapefruit. When asked why, she simply replied, “I’m on cholesterol medication .”
That wonderful, thick skinned, tangy yet sweet fruit that is also known as the forbidden fruit of Barbados and grows in clusters like grapes is well known for its interactions with multiple medications. Grapefruit contains certain chemical compounds called polyphenolics that inhibit the metabolism or break down of some medications, statins being one of the most notorious. Statins are highly effective and one of the most commonly prescribed cholesterol lowering medicines. This class of medication inhibits a liver enzyme and can lower LDL by ~50% and raise HDL . Drugs in the statin class in...
A reader recently asked if eating a significant amount of fiber can diminish the effect of Lipitor (atorvastatin) in reducing cholesterol levels. I am not aware of any negative effect of fiber on the absorption or the effects of the statins on lowering cholesterol. Statins including Lipitor can cause gastrointestinal side effects such as diarrhea and interestingly, constipation as well. The mechanism is not completely understood. What I am quite aware of is the overall positive effects of fiber in improving cholesterol levels including evidence to support that fiber can enhance a statin’s effectiveness. Fiber can improve cholesterol levels in several ways. One often overlooked benefit of eating fiber is that it can easily act as a substitute for a potential damaging food . For example, we know that we should minimize the intake of trans and saturated fats . But, we still need to eat something to satisfy our hunger as well as give us our daily supply of energy. If w...
You should knowAnswers to your question are meant to provide general health information but should not replace medical advice you receive from a doctor. No answers should be viewed as a diagnosis or recommended treatment for a condition. Content posted by community members does not necessarily reflect the views of Remedy Health Media, which also reserves the right to remove material deemed inappropriate.