Generic Name: NIACIN EXTENDED-RELEASE/SIMVASTATIN - ORAL Pronounced: (NYE-a-sin/SIM-va-STAT-in) Niacin-simvastatin Oral Precautions
Before taking this product, tell your doctor or pharmacist
if you are allergic to niacin or simvastatin; or if you have any other
allergies. This product may contain inactive ingredients, which can cause
allergic reactions or other problems. Talk to your pharmacist for more
Before using this medication, tell your doctor or
pharmacist your medical history, especially of:
Before having surgery, tell your doctor or dentist about
all the products you use (including prescription drugs, nonprescription drugs,
and herbal products).
This drug may make you dizzy. Do not drive, use machinery,
or do any activity that requires alertness until you are sure you can perform
My mother-in-law has been visiting with us for the past few weeks. She remarked one day while peeling a mango how she felt as if she had a kindred spirit with citrus fruit, but was quick to also mention how disappointed she was to learn that she is no longer able to eat grapefruit. When asked why, she simply replied, “I’m on cholesterol medication .”
That wonderful, thick skinned, tangy yet sweet fruit that is also known as the forbidden fruit of Barbados and grows in clusters like grapes is well known for its interactions with multiple medications. Grapefruit contains certain chemical compounds called polyphenolics that inhibit the metabolism or break down of some medications, statins being one of the most notorious. Statins are highly effective and one of the most commonly prescribed cholesterol lowering medicines. This class of medication inhibits a liver enzyme and can lower LDL by ~50% and raise HDL . Drugs in the statin class in...
Several days, ago, it was discussed in the New Jersey Star-Ledger. Then the New York Times. So I guess it's my turn. The New Jersey paper frequently reports and editorializes on drug company problems. No big surprise, as many drug companies are in NJ -- including Schering-Plough and Merck, who have had a recent egg-on-their-face episode with delayed reporting of a study involving Vytorin and Zetia. But then the New York Times chimed in the next day (April 2) with an editorial, Overpromoted Cholesterol Drugs . The Times editorialized that "It is distressingly late to be learning that these drugs may provide little or no benefit." Time to clear up the air... sorry, NY Times, but they do have benefit, although a small study came to inconclusive results about their effects on some biomarkers. Seems that Schering Plough and Merck have been co-marketing a combination drug for hyperlipidemia, called Vytorin. Vytorin is a combination of two ingredients: Zetia (ezetimibe) and Zocor (...
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