Generic Name: NIACIN EXTENDED-RELEASE/SIMVASTATIN - ORAL Pronounced: (NYE-a-sin/SIM-va-STAT-in) Niacin-simvastatin Oral Precautions
Before taking this product, tell your doctor or pharmacist
if you are allergic to niacin or simvastatin; or if you have any other
allergies. This product may contain inactive ingredients, which can cause
allergic reactions or other problems. Talk to your pharmacist for more
Before using this medication, tell your doctor or
pharmacist your medical history, especially of:
Before having surgery, tell your doctor or dentist about
all the products you use (including prescription drugs, nonprescription drugs,
and herbal products).
This drug may make you dizzy. Do not drive, use machinery,
or do any activity that requires alertness until you are sure you can perform
A reader recently asked if eating a significant amount of fiber can diminish the effect of Lipitor (atorvastatin) in reducing cholesterol levels. I am not aware of any negative effect of fiber on the absorption or the effects of the statins on lowering cholesterol. Statins including Lipitor can cause gastrointestinal side effects such as diarrhea and interestingly, constipation as well. The mechanism is not completely understood. What I am quite aware of is the overall positive effects of fiber in improving cholesterol levels including evidence to support that fiber can enhance a statin’s effectiveness. Fiber can improve cholesterol levels in several ways. One often overlooked benefit of eating fiber is that it can easily act as a substitute for a potential damaging food . For example, we know that we should minimize the intake of trans and saturated fats . But, we still need to eat something to satisfy our hunger as well as give us our daily supply of energy. If w...
Several days, ago, it was discussed in the New Jersey Star-Ledger. Then the New York Times. So I guess it's my turn. The New Jersey paper frequently reports and editorializes on drug company problems. No big surprise, as many drug companies are in NJ -- including Schering-Plough and Merck, who have had a recent egg-on-their-face episode with delayed reporting of a study involving Vytorin and Zetia. But then the New York Times chimed in the next day (April 2) with an editorial, Overpromoted Cholesterol Drugs . The Times editorialized that "It is distressingly late to be learning that these drugs may provide little or no benefit." Time to clear up the air... sorry, NY Times, but they do have benefit, although a small study came to inconclusive results about their effects on some biomarkers. Seems that Schering Plough and Merck have been co-marketing a combination drug for hyperlipidemia, called Vytorin. Vytorin is a combination of two ingredients: Zetia (ezetimibe) and Zocor (...
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