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Wednesday, December 03, 2008 susan, Community Member, asks

Q: compare Pravastatin with Crestor, please

I have recently been told to switch from Pravastatin to Crestor. Any advantages to one over the other? Different method of action?
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Answers (4)
Neil MD, Health Pro
12/ 6/08 6:49pm

Hello susan,


Not really.


Both medications are members of the statin family of cholesterol lowering drugs.  These drugs work by decreasing the amount of cholesterol the body produces from the fat we eat.


Crestor, or rosuvastatin in the generic, is considered a more potent statin than pravastatin.  If you were on the maximum dose of pravastatin but need additional cholesterol medication, your doctor may have switched you to Crestor to further reduce cholesterol levels (note that the increased reduction would likely be fairly modest).  Pravastatin is not metabolized by the liver as much and may be somewhat safer for people with liver diseases.


Other than that, both have similar side effects and both need to be monitored by yearly liver function tests.


To your health,

Neil MD

Alice Orshan, Community Member
5/10/09 4:42pm

compare pravastatin to crestor

Rhonda, Community Member
10/22/09 1:05am

I have never taken pravastatin. Since I have started taking Crestor my cholesterol has lowered by 100 points..around a year. Is pravastatin better? Does crestor have more side effects than pravastatin?

Susan, Community Member
6/ 9/10 7:22pm

If Crestor has been prescribed can i take Pravastain and get the same results?

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By susan, Community Member— Last Modified: 12/07/13, First Published: 12/03/08