Friday, June 01, 2012
Friday, November 04, 2011 jeffrey k hobbs asks

Q: ldl is 65 trys are 255, if I have pattern b ldl am I still at risk of cad with low ldl #

other #s are hdl 39, total 165. been in this range for last 8 years, 54 year old male.

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Answers (1)
11/ 5/11 1:28pm

People with pattern b LDL are at greater risk if their total pattern b LDL particles are over 30% of their total LDL. These smaller more dense LDL particles are better able to pass through artery linings or hold to artery wals and HDL is not as effective in binding with patter b LDL to remove it from your blood.

 

Here, this will explain more;

 

Here is an excerpt from the link below explaining why;

LDL B pattern particles;

--Are not cleared from the bloodstream as rapidly as the more normal large LDL particles, since the LDL receptor recognizes them less effectively. Small LDL of pattern B therefore hang around much longer, providing more opportunity to cause atherosclerotic plaque.

--Are more adherent to the artery wall, making them more likely to trigger plaque formation.

--Are more potent triggers of inflammatory responses of the sort that make atherosclerotic plaque grow.

--Are more prone to oxidation, making them more powerful triggers of inflammation.

--Are more prone to glycation, or the glucose-triggered modification of the apoprotein B that makes it much more likely to contribute to atherosclerotic plaque.  


http://www.healthcentral.com/cholesterol/c/7986/116328/ldl-pattern

 

Hope this helps,

 

Jon

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11/ 6/11 5:22am

Thanks jon, have been to that  site, the ? IS because the ldl is so low 65, does that help lessen the effects of the pattern b.  thanks

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By jeffrey k hobbs— Last Modified: 11/06/11, First Published: 11/04/11