- Bile acid-sequestering resins
- Fibrates (such as gemfibrozil)
Those with more severe forms of this disorder may need a treatment called extracorporeal apheresis. This is the most effective treatment. Blood or plasma is removed from the body. Special filters then remove the extra LDL-cholesterol, and the blood plasma is then returned.
How well you do greatly depends on whether or not you follow your doctor's treatment recommendations. Diet changes, exercise, and medications can lower cholesterol levels for those with the milder form of this disorder, and may significantly delay a heart attack.
Men and women with familial hypercholesterolemia typically are at increased risk of early heart attacks.
Risk of death varies among patients with familial hypercholesterolemia. Persons who inherit two copies of the defective gene have a poorer outcome. That type of familial hypercholesterolemia causes early heart attacks and is resistant to treatment.
- Heart attack at an early age
- Heart disease
Calling your health care provider
Seek immediate medical care if you have chest pain or other warning signs of heart attacks.
Call for an appointment with your health care provider if you have a personal or family history of high cholesterol levels.
Review Date: 05/23/2010
Reviewed By: David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc., and David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine.