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Monday, November 23, 2009
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Focal segmental glomerulosclerosis

Male urinary system
Male urinary system
Alternative Names

Segmental glomerulosclerosis; Focal sclerosis with hyalinosis


Treatment

Some patients will receive high doses of corticosteroids or a drug called cyclosporine. It is not clear, however, whether these drugs can prevent the kidneys from eventually failing.

The goal of treatment is to control the symptoms associated with nephrotic syndrome and chronic kidney failure.

See also:

  • Chronic kidney failure
  • Nephrotic syndrome

In general, treatments may include:

  • Antibiotics to control infections
  • Dialysis
  • Fluid restriction
  • Kidney transplantation
  • Low fat diet
  • Low or moderate protein diet (1 gram of protein per kilogram of body weight per day)
  • Medicines to treat high blood pressure, high blood cholesterol, and high triglyceride levels
  • Powerful anti-inflammatory medicines to reduce the immune response
  • Salt-free diet
  • Vitamin D supplementation

See also: Kidney disease - diet


Support Groups


Expectations (prognosis)

More than half of those with focal or segmental glomerulosclerosis develop chronic kidney failure within 10 years.


Complications
  • Chronic kidney failure
  • End-stage kidney disease
  • Infection
  • Malnutrition
  • Nephrotic syndrome

Calling your health care provider

You should call your doctor if you develop symptoms of this condition, especially if there is fever, pain with urination, or decreased urine output.



Review Date: 05/20/2009
Reviewed By: Parul Patel, MD, Private Practice specializing in Nephrology and Kidney and Pancreas Transplantation, Affiliated with California Pacific Medical Center, Department of Transplantation, San Francisco, CA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org).
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