Methadone deserves special attention and care.  Other medications are used for nerve pain in innovative ways that are usually "off label". Creative care is paramount for nerve pain which can be tricky to treat.

Nerve pain due to peripheral neuropathy or a central pain syndrome can be an unrelenting hot-poker, torture experience. In my experience, using a combination of medications at small doses is more effective than mono-therapy (a one drug, one problem approach). Sometimes it takes trial and error to find the right combination. At times, patients feel like guinea pigs. With patience and perseverance, a doctor can usually find the right combination of medications that douses the fire of nerve pain.

For those interested in reading my attempt at creatively describing nerve pain, please see my poem "My Nerve's On Fire".