Information and opinions on Chronic Pain from jbsquare at ChronicPainConnection.com. The HealthCentral Network, Inc. (www.HealthCentral.com) is one of the top health destinations on the Web, with more than 35 condition-specific, wellness and general health Web properties. http://www.healthcentral.com/chronic-pain/c/311983 http://www.healthcentral.com/chronic-pain/c/311983/rss self application/xml en-us 15 120 19 http://www.healthcentral.com/images/hc_logo_sm.gif http://www.healthcentral.com/chronic-pain/c/311983 http://www.healthcentral.com/chronic-pain/c/311983/94191/inhibitors Mon, 09 Nov 2009 20:28:36 -0500 jbsquare Does anyone know how SSRI's decrease pain?  I have read that sometimes they do and sometimes they don't.  But for me they did.  However, the side effects are so bad that I cannot take them.  If I could figure out the pain reducing mechanism of SSRI's, perhaps I could figure out another thing to try.   I don't know if the SSRI"s reduce pain because of the increased serotonin or something else.  I have tried to... http://www.healthcentral.com/chronic-pain/c/311983/94191/inhibitors