New Extended-Release Hydromorphone Approved

By Karen Lee Richards, Health Guide Wednesday, March 03, 2010
This week the FDA approved Exalgo, the first extended-release form of the opioid pain reliever hydromorphone.   Exalgo is for the treatment of moderate to severe chronic pain and can only be given to opioid-tolerant patients.  It will be available in 8 mg, 12 mg, and 16 mg dosages.&nbs...
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3/ 3/10 7:50am

Awesome news! And I really hope that the FDA is listening to us (finally!), let's hope that this is the beginning of a positive REMS turn around.

3/ 3/10 1:37pm

SO GLAD TO HEAR THAT FINALLY THERE MAY BE A NEW TIME RELEASE MED! I DON'T  KNOW THAT MUCH ABOUT HYDROMOPHONE IS. I WILL DO SOME RESEARH TO FIND OUT!  THANKS AGAIN TO KAREN!

3/ 3/10 5:09pm

I take morphine sulfate ER. I don't know how this will compare?

3/ 3/10 5:51pm

joanna, thank you for you reply! from what i have read thus far it is dillalid(i know the spelling is so wrong, hope you know what i mean) maybe someone can help with which one works best and side effects. i have never been able to take oxcycotin.i am on  the highest dose of hydrcodone now, take the edge off that is all.              thanks for the reply hope you are having a good day! best wishes.

Karen Lee Richards, Health Guide
3/ 3/10 10:49pm

You're right.  Exalgo is the same thing as Dilaudid.  Several years ago the company that made Dilaudid started working on an extended-release version that was to be called Dilaudid CR (for continuous release).  Over the years, the company changed hands several times and each time the extended-release hydromorphone product they were trying to get approved was renamed.  Now the company is owned by Covidien and they have named the medication Exalgo – and it was finally approved. 

Anonymous
SherryJohnson64
3/ 4/10 8:41am

This is the best news I've heard in a long time! I had been taking Dilaudid for about 7 years. Having malabsorbtion from gastric bypass surgery in addition to a high tolerance level from taking it for so long, I was taking two 8mg tablets 4 times/day. While that was an extremely high dosage, it worked well for me... I was able to continue working an extra year... and I didn't experience any side effects at all. Then suddenly the generic form was back ordered and/or out of stock everywhere I went and it seemed to be unavailable. I have not been able to find a replacement that works as well or without bad side effects. I can't wait to talk to my pain management specialist about this development! How soon will it be available? Thank you so much for sharing this information!  :-)

3/ 4/10 12:18pm

It is a brand vs a generic. It's made out of the same ingredient as Dilaudid. I had the chance to participate in the study, but with my condition, it was too far for me to take the trip. However, I'm pleased that the regulators are taking pain management seriously.

Karen Lee Richards, Health Guide
3/ 5/10 3:54pm

I haven't been able to find a specific date that it will be available yet.  All I could find was a statement that they expect to begin marketing it in the next few weeks.  Hopefully it won't be too much longer. 

3/22/10 11:56am

I've been taking dilaudid for over a year and this is great news bec ause for me the side effects are greatly reduced from morphine cr,especially , nausea and constipation.

3/22/10 1:00pm

I use to be on 60mg oxycotin 3 times day with 8mg hydromorphone 5 times a day for pain from injuries I got from serving in the navy and also from a car wreak. I have a plate and bone fusion in my neck. Also injuries to lower back and legs, which has devolped arthris. I am trying now the steriods shot again but in lower back only. They don't work that well. I have try everything to rid myself from pain, but found only the stong pain meds work. This a problem in its self, having to take so much medicine all the time. But this new med may work better longer, which in my book is good news.

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By Karen Lee Richards, Health Guide— Last Modified: 01/15/12, First Published: 03/03/10