FDA Alert: Topamax Taken During Early Pregnancy Increases Risk of Cleft Defects

Karen Lee Richards Health Guide
  • The FDA has issued a new warning about the use of Topamax (topiramate) during pregnancy.  Topamax is an anticonvulsant medication also approved for Migraine prevention.  Like other anticonvulsants, Topamax is sometimes used off-label for chronic pain – particularly neuropathic or nerve pain. 

    New information from the North American Antiepileptic Drug (AED) Pregnancy Registry shows an increased risk of oral clefts (cleft lip and cleft palate) in infants exposed to topiramate during the first trimester of pregnancy. 

    For more information about this warning, please read this article by Teri Robert, Lead Expert on our sister site MyMigraineConnection.comPregnancy and Migraines: Topamax Warning, Cleft Defects

    Add This Infographic to Your Website or Blog With This Code:

Published On: March 08, 2011