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I hope this is a new hope
c
Thursday, December 04, 2008 at 09:44 PMre: I hope this is a new hope
Karen Lee Richards
Friday, December 05, 2008 at 11:52 PMYou ask some good questions. From what I could find out, there is a fairly high amount of salt in sodium oxybate. It warns that you should tell your doctor before taking it if you have heart disease, high blood pressure, kidney disease, liver disease, and a number of other conditions.
Sodium oxybate is a central nervous depressant and has been on the market under the brand name Xyrem since 2002. It has FDA approval for use in the treatment of cataplexy and to reduce daytime sleepiness in narcolepsy patients. It's a Schedule III drug and is carefully monitored because of its potential for abuse.
I'll be interested in watching it over the next year to see how the second Phase III clinical trials go as a possible FM treatment. I'm not sure it would be my first choice to try, but hopefully it will help some FM patients who have not been helped by the other options currently on the market.
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The only questions I would have would be, what about people with high blood pressure and who are already trying to lower their sodium intake? What are the long term effects, not just with all the nasty things associated with having a high sodium intake but in general? It does not sound like 'they' did any long term studies. Will wait and hope as always...thank you for this piece.
C