• lab71 lab71
    May 11, 2008
    how long does a percocet 10 mg stay in your blood system?
    lab71 lab71
    May 11, 2008


  • Karen Lee Richards
    Health Guide
    May 12, 2008
    Karen Lee Richards
    Health Guide
    May 11, 2008

    The oxycodone portion of percocet has a half-life of 3.2 hours for the regular version and 4.5 hours for the extended release version.  (The half-life of a medication is the time it takes for your body to metabolize and excrete a drug so that half of the drug is removed from your body.)  As a general rule you are considered fully clean in blood and urine after 5 half lives. So for regular percocet, that would be 16 hrs. and 22.5 for extended release. 


    Keep in mind that the half of every drug varies greatly.  Half-life can also vary from patient to patient if the patient suffers from altered kidney or liver function.  For a more accurate estimate for a specific medication, check with your pharmacist. 




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