Tuesday, October 21, 2014

Sunday, July 06, 2008 mb, Community Member, asks

Q: why does percocet make me itch?

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Answers (2)
Cort, Health Guide
7/ 7/08 11:39am

Itching is a sign that you may be having an allergic reaction to Percocet. The itching itself is not the problem the problem is that the itching could be a precursor to a serious possibly even life threatening allergic. You should immediately inform your doctor of this problem. You may be having a reaction to the acetaminophen in the drug.


Other allergic symptoms include swelling, trouble breathing, rash, tingling and numbness and dizziness.


You can find out more about Percocet at http://www.healthcentral.com/chronic-pain/find-drug-113368-73.html



steaksofttaco, Community Member
10/ 4/09 2:14am

before succombing to the scare post of the previous person who replied to your question, taker note that one of the side effects of opiates is the release of histamine.  Histamine is what is causing the itchy sensations (pruritis - which is listed as one of themain side effects of oxycodone).  Taking an over the counter antihistamine, such as Benadryl, will usually make it go away.  Of course, consult your doctor prior to taking any other medication with your pain medications.

Helen, Community Member
6/ 5/14 10:31am

Thank u. I believe this because I'm usually on antihistamines but haven't taken one today.

Karen Lee Richards, Health Guide
10/ 9/10 1:25am

A true allergy to an opioid is very rare.  It is common, however, to itch when taking an opioid due to the histamine release.  An over-the-counter antihistamine will usually take care of it.  Sometimes after you've been taking the medication for awhile, the itching will go away on its own.


If the itching bothers you too much and an antihistamine doesn't help, you might talk with your doctor about switching you to an opioid in a different chemical class.

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By mb, Community Member— Last Modified: 06/05/14, First Published: 07/06/08