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Dear Dr. Motola,
If a person has a low PSA can you attribute this to any particular factor or factors? In other words are there any medical reasons for a low PSA? A friend told me that there has to be mitigating factors for this low score.
A low PSA is usually desirable as it will be associated with a lower likelihood of prostate cancer . Prostate cancer is not always associated with an elevated PSA as tumors that are very high grade may be associated with normal PSA . This occurs because high-grade tumors are very dissimilar to normal prostate, and as a result lose their ability to secrete PSA. Most often these patients will have very abnormal digital rectal examination. Patients taking Proscar or Avodart may often have low PSA values. This group of patients needs to have careful scrutiny of the interpretation of their PSA.
You want to control your diabetes as much as possible. You wouldn't be reading this if you didn't. So you regularly check your A1C level. This is the best measurement of our blood glucose control that we have now. It tells us what percentage of our hemoglobin -- the protein in our red blood cells that carry oxygen -- has glucose sticking to it. The less glucose that remains in our bloodstream rather than going to work in the cells that need it the better we feel now and the better our health will continue to be. As we are able to control our diabetes better and better, the reasonable goal is to bring our A1C levels down to normal -- the A1C level that people who don't have diabetes have. But before we can even set that goal, we have to know what the target is. The trouble with setting that target is that different experts tell us that quite different A1C levels are "normal." They tell us that different levels are normal -- but I have never heard of actual studies of normal A1C leve...
Alternative Names Serum angiotensin-converting enzyme; SACE Normal Values Normal values vary based on your age and the test method used. Typically, adults have ACE levels less than 40 micrograms/L. Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results. What abnormal results mean Increased ACE levels may be a sign of sarcoidosis. However, increased ACE levels may also be seen in several other disorders, including: Active histoplasmosis Amyloidosis Asbestosis Berylliosis Diabetes Emphysema Gaucher's disease Hepatitis Hodgkin's disease Hyperthyroidism Idiopathic pulmonary fibrosis Leprosy Lung cancer Nephrotic syndrome Primary biliary cirrhosis Pulmonary embolism Scleroderma Silicosis Tuberculosis A decrease in ACE levels may indicate: Steroid therapy (usually prednisone) Therapy for sarcoidosis
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