Enbrel causing Drug induced Lupus?
I have just been told by my Rheumy that I have Lupus and she feels it's due to my use (2 1/2 yrs) of Enbrel. Has anyone had this happen or heard of it happening? I was taking the Enbrel because of the Psoriatic Arthritis I have. I also have Fibromyalgia and the list seems to be getting longer. Not right!!
Thanks for any insight!
Laurie in NY
From page 22 of the prescribing information for Enbrel:
Autoimmunity
Treatment with ENBREL® may result in the formation of autoantibodies (see ADVERSE REACTIONS: Autoantibodies) and, rarely, in the development of a lupus-like syndrome or autoimmune hepatitis (see ADVERSE REACTIONS: Adverse Reaction Information from Spontaneous Reports), which may resolve following withdrawal of ENBREL®. If a patient develops symptoms and findings suggestive of a lupus-like syndrome or autoimmune hepatitis following treatment with ENBREL®, treatment should be discontinued and the patient should be carefully evaluated.
You can find this information on the Enbrel site, http://www.enbrel.com/pdf/enbrel_pi.pdf.
Sorry,
Teri
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Yes, it happens more that Dr's admit. I developed Lupus Syndrome on Remicade, with liver enzymes elevated sky high, chronic kidney infections, unrelenting pain body wide bi-laterally, developed anti bodies, anticardiolipid antibodies. It took eighteen months of miserable pain, night sweats, etc,etc, for the symptoms to subside. My doctor appeared bewildered, and gave no support or validation to my symptoms. There's more if you are wanting more info. Anyway that was 4 years ago. So how quickly we can forget these issues. I went on Enbrel in December 2008, well it finally dawned on me why I am in severe body wide pain again, Here I was thinking we've had a bad winter and no pain relief with enbrel and the other significant pain control drugs that are in my treatment plan. they are the exact symptoms I had with the Remicade. These drugs should be used very judicially. My thinking is I've had this mixed connective tissue disease all along and have inflamatory arthritis and Fibro diagnosis. It seems that you have an honest Dr. that has not blown off the lupus syndrome like my Dr. did. I hope your symptoms subside in a fair amount of time,
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